Genetic Factors Associated with Toe Walking in Children

The article describes genetic factors associated with toe walking in children. Association of gait abnormality with variants in genes listed below is shown: PMP22 (peripheral myelin protein 22), EGR2 (early growth response protein 2), AIFM1 (apoptosis inducing factor mitochondria associated 1), MORC...

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Main Authors: David Pomarino, Anneke Thren, Stefaine Morigeau, Johanna R. Thren, Anna A. Emelina
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2020-06-01
Series:Вопросы современной педиатрии
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Online Access:https://vsp.spr-journal.ru/jour/article/view/2381
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author David Pomarino
Anneke Thren
Stefaine Morigeau
Johanna R. Thren
Anna A. Emelina
author_facet David Pomarino
Anneke Thren
Stefaine Morigeau
Johanna R. Thren
Anna A. Emelina
author_sort David Pomarino
collection DOAJ
description The article describes genetic factors associated with toe walking in children. Association of gait abnormality with variants in genes listed below is shown: PMP22 (peripheral myelin protein 22), EGR2 (early growth response protein 2), AIFM1 (apoptosis inducing factor mitochondria associated 1), MORC2 (member of the Microrchidia family CW-type zinc finger 2), DHTKD1 (dehydrogenase E1 and transketolase domain containing 1), GDAP1 (ganglioside induced differentiation associated protein 1), KIF1B (kinesin family member 1B), FGD4 (FYVE, RhoGEF and PH domain containing 4), SBF2 (SET binding factor 2), SH3TC2 (SH3 domain and tetratricopeptide repeats 2), NAGLU (N-acetyl-alpha-glucosaminidase), NEFL (neurofilament light) и PRX (periaxin). Genetic testing of patients with toe walking is crucial for accurate diagnostics of this pathology as well as clinical examination.
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publisher "Paediatrician" Publishers LLC
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series Вопросы современной педиатрии
spelling doaj-art-ce67830179d4418391a060a67fa31d6c2025-08-20T03:21:55Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352020-06-0119214614910.15690/vsp.v19i2.21081875Genetic Factors Associated with Toe Walking in ChildrenDavid Pomarino0Anneke Thren1Stefaine Morigeau2Johanna R. Thren3Anna A. Emelina4Praxis PomarinoPraxis PomarinoPraxis PomarinoPraxis PomarinoSamara State Medical UniversityThe article describes genetic factors associated with toe walking in children. Association of gait abnormality with variants in genes listed below is shown: PMP22 (peripheral myelin protein 22), EGR2 (early growth response protein 2), AIFM1 (apoptosis inducing factor mitochondria associated 1), MORC2 (member of the Microrchidia family CW-type zinc finger 2), DHTKD1 (dehydrogenase E1 and transketolase domain containing 1), GDAP1 (ganglioside induced differentiation associated protein 1), KIF1B (kinesin family member 1B), FGD4 (FYVE, RhoGEF and PH domain containing 4), SBF2 (SET binding factor 2), SH3TC2 (SH3 domain and tetratricopeptide repeats 2), NAGLU (N-acetyl-alpha-glucosaminidase), NEFL (neurofilament light) и PRX (periaxin). Genetic testing of patients with toe walking is crucial for accurate diagnostics of this pathology as well as clinical examination.https://vsp.spr-journal.ru/jour/article/view/2381idiopathic toe walkinggait abnormalitypes cavusinheritancegenes
spellingShingle David Pomarino
Anneke Thren
Stefaine Morigeau
Johanna R. Thren
Anna A. Emelina
Genetic Factors Associated with Toe Walking in Children
Вопросы современной педиатрии
idiopathic toe walking
gait abnormality
pes cavus
inheritance
genes
title Genetic Factors Associated with Toe Walking in Children
title_full Genetic Factors Associated with Toe Walking in Children
title_fullStr Genetic Factors Associated with Toe Walking in Children
title_full_unstemmed Genetic Factors Associated with Toe Walking in Children
title_short Genetic Factors Associated with Toe Walking in Children
title_sort genetic factors associated with toe walking in children
topic idiopathic toe walking
gait abnormality
pes cavus
inheritance
genes
url https://vsp.spr-journal.ru/jour/article/view/2381
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AT stefainemorigeau geneticfactorsassociatedwithtoewalkinginchildren
AT johannarthren geneticfactorsassociatedwithtoewalkinginchildren
AT annaaemelina geneticfactorsassociatedwithtoewalkinginchildren