Neurobiological Changes Associated with Excess Weight: A Narrative Review
Brain and neuronal changes related to excessive weight and obesity is critical due to address, given the rising global prevalence of obesity and its significant impact on neurological health. Obesity is associated with significant neuronal changes that can have profound effects on brain structure an...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2025-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/20542/76172_CE[Ra1]_F(SHU)_QC(SD_SHU)_PF1(RI_SL)_redo_PFA(IS)_PB(RI_IS)_PN(IS).pdf |
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| Summary: | Brain and neuronal changes related to excessive weight and obesity is critical due to address, given the rising global prevalence of obesity and its significant impact on neurological health. Obesity is associated with significant neuronal changes that can have profound effects on brain structure and function. These neuronal changes highlight the complex interplay between obesity and brain function, emphasising the importance of addressing both physical and neurological aspects of obesity in treatment and prevention strategies. Early reviews have often overlooked the intricate relationship between obesity and brain function, focusing more on peripheral effects, such as cardiovascular and metabolic complications, while neglecting the specific effects on brain structure and function. The present review explores the research question of how does excess weight contribute to specific structural and functional changes in brain regions involved in cognitive control, reward processing and memory and what are the implications of these changes for clinical outcomes and obesity management. It focuses on the clinical implications of neural changes in the context of obesity management. The analysis provides a comprehensive understanding of the underlying mechanisms driving these brain modifications and their potential impacts on clinical outcomes. |
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| ISSN: | 2249-782X 0973-709X |