Construction and validation of acetylation-related gene signatures for immune landscape analysis and prognostication risk prediction in luminal breast cancer

Construction and validation of acetylation-related gene signatures for immune landscape analysis and prognostication risk prediction in luminal breast cancer

Abstract Background Epigenetic acetylation plays an essential role in the development and drug resistance of luminal breast cancer. However, the acetylation regulatory network in luminal breast cancer remains underexplored. Methods We used the TCGA-BRCA database to explore the acetylation regulatory...

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Bibliographic Details
Main Authors: Mengdi Zhu, Jinna Lin, Haohan Liu, Jingru Wang, Nianqiu Liu, Yudong Li, Hongna Lai, Qianfeng Shi
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cancer Cell International
Subjects:
Acetylation
Luminal breast cancer
Prognostic signature
CD8 + T cell
Microenvironment.
Online Access:https://doi.org/10.1186/s12935-025-03920-w
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