Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response
Overweight and obesity are increasing worldwide and now reach about one-third of the world's population. Obesity also involves patients with inflammatory arthritis. Knowing the impact of obesity on rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis) is thus...
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Format: | Article |
Language: | English |
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BMJ Publishing Group
2015-06-01
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Series: | RMD Open |
Online Access: | https://rmdopen.bmj.com/content/1/1/e000012.full |
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author | Jérémie Sellam Claire I Daien |
author_facet | Jérémie Sellam Claire I Daien |
author_sort | Jérémie Sellam |
collection | DOAJ |
description | Overweight and obesity are increasing worldwide and now reach about one-third of the world's population. Obesity also involves patients with inflammatory arthritis. Knowing the impact of obesity on rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis) is thus an important issue. This article first reviews the epidemiological and clinical data available on obesity in inflammatory rheumatic diseases, that is, its impact on incident disease, disease characteristics and the therapeutic response. The second part of this review gives an overview of the factors potentially involved in the specifics of inflammatory arthritis in patients with obesity, such as limitations in the clinical assessment, diet, microbiota and adipokines. |
format | Article |
id | doaj-art-ce3e28d557cb4fb78ffe5c823e257ab9 |
institution | Kabale University |
issn | 2056-5933 |
language | English |
publishDate | 2015-06-01 |
publisher | BMJ Publishing Group |
record_format | Article |
series | RMD Open |
spelling | doaj-art-ce3e28d557cb4fb78ffe5c823e257ab92025-02-03T07:55:09ZengBMJ Publishing GroupRMD Open2056-59332015-06-011110.1136/rmdopen-2014-000012Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic responseJérémie Sellam0Claire I Daien1Centre de Recherche Saint-Antoine, INSERM UMR_S 938, Sorbonne Universite, Paris, Île-de-France, FranceRheumatology Department, Teaching Hospital of Montpellier and UMR5535, CNRS, Institut de Génétique Moléculaire, Montpellier, FranceOverweight and obesity are increasing worldwide and now reach about one-third of the world's population. Obesity also involves patients with inflammatory arthritis. Knowing the impact of obesity on rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis) is thus an important issue. This article first reviews the epidemiological and clinical data available on obesity in inflammatory rheumatic diseases, that is, its impact on incident disease, disease characteristics and the therapeutic response. The second part of this review gives an overview of the factors potentially involved in the specifics of inflammatory arthritis in patients with obesity, such as limitations in the clinical assessment, diet, microbiota and adipokines.https://rmdopen.bmj.com/content/1/1/e000012.full |
spellingShingle | Jérémie Sellam Claire I Daien Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response RMD Open |
title | Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response |
title_full | Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response |
title_fullStr | Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response |
title_full_unstemmed | Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response |
title_short | Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response |
title_sort | obesity and inflammatory arthritis impact on occurrence disease characteristics and therapeutic response |
url | https://rmdopen.bmj.com/content/1/1/e000012.full |
work_keys_str_mv | AT jeremiesellam obesityandinflammatoryarthritisimpactonoccurrencediseasecharacteristicsandtherapeuticresponse AT claireidaien obesityandinflammatoryarthritisimpactonoccurrencediseasecharacteristicsandtherapeuticresponse |