Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response

Overweight and obesity are increasing worldwide and now reach about one-third of the world's population. Obesity also involves patients with inflammatory arthritis. Knowing the impact of obesity on rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis) is thus...

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Main Authors: Jérémie Sellam, Claire I Daien
Format: Article
Language:English
Published: BMJ Publishing Group 2015-06-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/1/1/e000012.full
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author Jérémie Sellam
Claire I Daien
author_facet Jérémie Sellam
Claire I Daien
author_sort Jérémie Sellam
collection DOAJ
description Overweight and obesity are increasing worldwide and now reach about one-third of the world's population. Obesity also involves patients with inflammatory arthritis. Knowing the impact of obesity on rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis) is thus an important issue. This article first reviews the epidemiological and clinical data available on obesity in inflammatory rheumatic diseases, that is, its impact on incident disease, disease characteristics and the therapeutic response. The second part of this review gives an overview of the factors potentially involved in the specifics of inflammatory arthritis in patients with obesity, such as limitations in the clinical assessment, diet, microbiota and adipokines.
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spelling doaj-art-ce3e28d557cb4fb78ffe5c823e257ab92025-02-03T07:55:09ZengBMJ Publishing GroupRMD Open2056-59332015-06-011110.1136/rmdopen-2014-000012Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic responseJérémie Sellam0Claire I Daien1Centre de Recherche Saint-Antoine, INSERM UMR_S 938, Sorbonne Universite, Paris, Île-de-France, FranceRheumatology Department, Teaching Hospital of Montpellier and UMR5535, CNRS, Institut de Génétique Moléculaire, Montpellier, FranceOverweight and obesity are increasing worldwide and now reach about one-third of the world's population. Obesity also involves patients with inflammatory arthritis. Knowing the impact of obesity on rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis) is thus an important issue. This article first reviews the epidemiological and clinical data available on obesity in inflammatory rheumatic diseases, that is, its impact on incident disease, disease characteristics and the therapeutic response. The second part of this review gives an overview of the factors potentially involved in the specifics of inflammatory arthritis in patients with obesity, such as limitations in the clinical assessment, diet, microbiota and adipokines.https://rmdopen.bmj.com/content/1/1/e000012.full
spellingShingle Jérémie Sellam
Claire I Daien
Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response
RMD Open
title Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response
title_full Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response
title_fullStr Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response
title_full_unstemmed Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response
title_short Obesity and inflammatory arthritis: impact on occurrence, disease characteristics and therapeutic response
title_sort obesity and inflammatory arthritis impact on occurrence disease characteristics and therapeutic response
url https://rmdopen.bmj.com/content/1/1/e000012.full
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AT claireidaien obesityandinflammatoryarthritisimpactonoccurrencediseasecharacteristicsandtherapeuticresponse