TLR4 deficiency does not alter glaucomatous progression in a mouse model of chronic glaucoma
Abstract Glaucoma is a leading cause of irreversible blindness worldwide. Toll-like receptor 4 (TLR4) is a pattern-recognition transmembrane receptor that induces neuroinflammatory processes in response to injury. Tlr4 is highly expressed in ocular tissues and is known to modulate inflammatory proce...
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| Main Authors: | Chi Zhang, Marina Simón, Jeffrey M. Harder, Haeyn Lim, Christa Montgomery, Qing Wang, Simon W.M. John |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-00638-7 |
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