High Glucose-Induced Senescent Fibroblasts-Derived Exosomal miR-497 Inhibits Wound Healing by Regulating Endothelial Cellular Autophagy via ATG13

High Glucose-Induced Senescent Fibroblasts-Derived Exosomal miR-497 Inhibits Wound Healing by Regulating Endothelial Cellular Autophagy via ATG13

Conclusions: Our study demonstrated that exosomes from senescent fibroblasts can impair endothelial cell function and impede diabetic wound healing. The underlying mechanism was that fibroblast-derived exosomal miR-497 can target ATG13 to reduce autophagy, offering insight into new therapy for diabe...

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Bibliographic Details
Main Authors: Changjiang Liu, Yuting Liu, Yifeng Yu, Siyuan Huang, Chao Sun, Dong Zhang, Aixi Yu
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/ancp/8890200
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