Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger Finger

Purpose: Triamcinolone tendon sheath injection is a useful nonsurgical treatment for trigger finger; however, complications, such as tendon rupture, and infections caused by excessive administration, have been reported. Considering the complication risk, we inject 4 mg triamcinolone into the tendon...

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Main Authors: Jo Watanabe, MD, PhD, Yusuke Matsuura, MD, PhD, Takahiro Yamazaki, MD, PhD, Toshiyuki Yamada, MD, PhD, Seiji Ohtori, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Hand Surgery Global Online
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589514125000064
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author Jo Watanabe, MD, PhD
Yusuke Matsuura, MD, PhD
Takahiro Yamazaki, MD, PhD
Toshiyuki Yamada, MD, PhD
Seiji Ohtori, MD, PhD
author_facet Jo Watanabe, MD, PhD
Yusuke Matsuura, MD, PhD
Takahiro Yamazaki, MD, PhD
Toshiyuki Yamada, MD, PhD
Seiji Ohtori, MD, PhD
author_sort Jo Watanabe, MD, PhD
collection DOAJ
description Purpose: Triamcinolone tendon sheath injection is a useful nonsurgical treatment for trigger finger; however, complications, such as tendon rupture, and infections caused by excessive administration, have been reported. Considering the complication risk, we inject 4 mg triamcinolone into the tendon sheath without limitation on the number of injections at intervals of at least 1 month. This study aimed to retrospectively examine the results of triamcinolone tendon sheath injections for trigger finger at multiple facilities. Methods: The participants included patients with trigger finger who visited four facilities between April 2009 and October 2021, received at least one triamcinolone tendon sheath injection, and could be evaluated for effectiveness. Patients with a follow-up period of <3 months from the initial injection, and pediatric patients aged <16 years old were excluded. Quinnell’s severity classification, number of injections per finger, interval of injections (when performed ≥2 times), complications, proportion of diabetes, hemoglobin A1c (HbA1c) levels, and proportion that required surgery were collected. Results: Overall, 356 cases and 715 fingers were included (men, 260 fingers; women, 455 fingers). The mean age of the participants was 64.9 years (17–92 years), and the mean number of affected fingers per person was 1.9 (1–7 fingers). The median follow-up period was 27 (3–134) months. According to Quinnell’s severity classification, 234, 274, 126, and 50 fingers were classified as grade 1, 2, 3, and 4, respectively. The average number of injections per finger was 3.3. The mean interval between injections was 6.3 months. Complications, such as tendon rupture, or infection, were not observed. The rate of diabetes was 22.4%, and the median HbA1c value was 7.2%. In total, 9.8% of all patients required surgery. Conclusions: No complications were observed for 4 mg triamcinolone injections when administered at intervals of at least 1 month. Type of study/level of evidence: Therapeutic Ⅳ.
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spelling doaj-art-ce38eda0b8804cb8bd55f75ee992c7732025-08-20T02:52:23ZengElsevierJournal of Hand Surgery Global Online2589-51412025-03-017222523110.1016/j.jhsg.2025.01.005Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger FingerJo Watanabe, MD, PhD0Yusuke Matsuura, MD, PhD1Takahiro Yamazaki, MD, PhD2Toshiyuki Yamada, MD, PhD3Seiji Ohtori, MD, PhD4Department of Orthopaedic Surgery, Matsudo City General Hospital, Matsudo, Chiba, Japan; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba, Japan; Corresponding author: Jo Watanabe, MD, PhD, Department of Orthopaedic Surgery, Matsudo City General Hospital, 993-1, Sendabori, Matsudo city, Chiba 270-2296, Japan.Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba, Japan; Department of Orthopaedic Surgery, Eastern Chiba Medical Center, Togane, Chiba, JapanDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba, JapanDepartment of Orthopaedic Surgery, Chiba Aoba Municipa Hospital, Chuo-ku, Chiba, JapanDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba, JapanPurpose: Triamcinolone tendon sheath injection is a useful nonsurgical treatment for trigger finger; however, complications, such as tendon rupture, and infections caused by excessive administration, have been reported. Considering the complication risk, we inject 4 mg triamcinolone into the tendon sheath without limitation on the number of injections at intervals of at least 1 month. This study aimed to retrospectively examine the results of triamcinolone tendon sheath injections for trigger finger at multiple facilities. Methods: The participants included patients with trigger finger who visited four facilities between April 2009 and October 2021, received at least one triamcinolone tendon sheath injection, and could be evaluated for effectiveness. Patients with a follow-up period of <3 months from the initial injection, and pediatric patients aged <16 years old were excluded. Quinnell’s severity classification, number of injections per finger, interval of injections (when performed ≥2 times), complications, proportion of diabetes, hemoglobin A1c (HbA1c) levels, and proportion that required surgery were collected. Results: Overall, 356 cases and 715 fingers were included (men, 260 fingers; women, 455 fingers). The mean age of the participants was 64.9 years (17–92 years), and the mean number of affected fingers per person was 1.9 (1–7 fingers). The median follow-up period was 27 (3–134) months. According to Quinnell’s severity classification, 234, 274, 126, and 50 fingers were classified as grade 1, 2, 3, and 4, respectively. The average number of injections per finger was 3.3. The mean interval between injections was 6.3 months. Complications, such as tendon rupture, or infection, were not observed. The rate of diabetes was 22.4%, and the median HbA1c value was 7.2%. In total, 9.8% of all patients required surgery. Conclusions: No complications were observed for 4 mg triamcinolone injections when administered at intervals of at least 1 month. Type of study/level of evidence: Therapeutic Ⅳ.http://www.sciencedirect.com/science/article/pii/S2589514125000064Steroid injectionsTrigger finger
spellingShingle Jo Watanabe, MD, PhD
Yusuke Matsuura, MD, PhD
Takahiro Yamazaki, MD, PhD
Toshiyuki Yamada, MD, PhD
Seiji Ohtori, MD, PhD
Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger Finger
Journal of Hand Surgery Global Online
Steroid injections
Trigger finger
title Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger Finger
title_full Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger Finger
title_fullStr Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger Finger
title_full_unstemmed Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger Finger
title_short Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger Finger
title_sort safety and efficacy of low dose triamcinolone injection without injection frequency limitation for trigger finger
topic Steroid injections
Trigger finger
url http://www.sciencedirect.com/science/article/pii/S2589514125000064
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