Inhaled Antibiotics in the Treatment of Nosocomial Pneumonia
Nosocomial pneumonia is the most common nosocomial infection in intensive care units. Rational antibiotic therapy is the basis for the treatment of nosocomial pneumonia. There is currently a challenge of the pathogens of nosocomial pneumonia being resistant to most of the antibiotics recommended for...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2013-12-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/92 |
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| author | A. N. Kuzovlev V. V. Moroz A. M. Golubev S. G. Polovnikov |
| author_facet | A. N. Kuzovlev V. V. Moroz A. M. Golubev S. G. Polovnikov |
| author_sort | A. N. Kuzovlev |
| collection | DOAJ |
| description | Nosocomial pneumonia is the most common nosocomial infection in intensive care units. Rational antibiotic therapy is the basis for the treatment of nosocomial pneumonia. There is currently a challenge of the pathogens of nosocomial pneumonia being resistant to most of the antibiotics recommended for its treatment. Inhaled antibiotics used in combination with systemic drugs are an effective and safe treatment for nosocomial pneumonia. This review of literature characterizes the current possibilities of inhaled antibiotic therapy for nosocomial pneumonia in detail and describes medicaments and the advantages and disadvantages of this treatment option. Despite insufficient evidence in circumstances where the microorganisms are polyresistant and where the design of novel antibiotics shows no promise, the use of inhaled antibiotics is an important alternative in the treatment of severe nosocomial pneumonia caused by polyresistant gram-negative bacteria. Key words: nosocomial pneumonia, antibiotic therapy, inhaled antibiotics, resistance. |
| format | Article |
| id | doaj-art-ce2ede481cc648cf8007a1b9d7bd9f77 |
| institution | Kabale University |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2013-12-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-ce2ede481cc648cf8007a1b9d7bd9f772025-08-20T03:35:08ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102013-12-019610.15360/1813-9779-2013-6-6192Inhaled Antibiotics in the Treatment of Nosocomial PneumoniaA. N. KuzovlevV. V. MorozA. M. GolubevS. G. PolovnikovNosocomial pneumonia is the most common nosocomial infection in intensive care units. Rational antibiotic therapy is the basis for the treatment of nosocomial pneumonia. There is currently a challenge of the pathogens of nosocomial pneumonia being resistant to most of the antibiotics recommended for its treatment. Inhaled antibiotics used in combination with systemic drugs are an effective and safe treatment for nosocomial pneumonia. This review of literature characterizes the current possibilities of inhaled antibiotic therapy for nosocomial pneumonia in detail and describes medicaments and the advantages and disadvantages of this treatment option. Despite insufficient evidence in circumstances where the microorganisms are polyresistant and where the design of novel antibiotics shows no promise, the use of inhaled antibiotics is an important alternative in the treatment of severe nosocomial pneumonia caused by polyresistant gram-negative bacteria. Key words: nosocomial pneumonia, antibiotic therapy, inhaled antibiotics, resistance.https://www.reanimatology.com/rmt/article/view/92 |
| spellingShingle | A. N. Kuzovlev V. V. Moroz A. M. Golubev S. G. Polovnikov Inhaled Antibiotics in the Treatment of Nosocomial Pneumonia Общая реаниматология |
| title | Inhaled Antibiotics in the Treatment of Nosocomial Pneumonia |
| title_full | Inhaled Antibiotics in the Treatment of Nosocomial Pneumonia |
| title_fullStr | Inhaled Antibiotics in the Treatment of Nosocomial Pneumonia |
| title_full_unstemmed | Inhaled Antibiotics in the Treatment of Nosocomial Pneumonia |
| title_short | Inhaled Antibiotics in the Treatment of Nosocomial Pneumonia |
| title_sort | inhaled antibiotics in the treatment of nosocomial pneumonia |
| url | https://www.reanimatology.com/rmt/article/view/92 |
| work_keys_str_mv | AT ankuzovlev inhaledantibioticsinthetreatmentofnosocomialpneumonia AT vvmoroz inhaledantibioticsinthetreatmentofnosocomialpneumonia AT amgolubev inhaledantibioticsinthetreatmentofnosocomialpneumonia AT sgpolovnikov inhaledantibioticsinthetreatmentofnosocomialpneumonia |