Limited efficacy of cold and heat therapy as adjunctive treatments for local and functional outcomes of Bothrops atrox snakebite envenomation: A randomized clinical trial.

Limited efficacy of cold and heat therapy as adjunctive treatments for local and functional outcomes of Bothrops atrox snakebite envenomation: A randomized clinical trial.

<h4>Background</h4>Bothrops atrox envenomation can cause significant local and systemic effects. Adjunctive therapies, such as cold and heat applications, are proposed to enhance antivenom efficacy, but their clinical value remains unclear.<h4>Methods</h4>This randomized, thr...

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Main Authors: Mailma Costa de Almeida, Kathleen Maclenny Pereira Carvalho, Yasmim da Silva Mendes, Debora Nery Oliveira, Érica da Silva Carvalho, Marco Aurélio Sartim, Felipe Queiroz Araújo, André Sachett, João Ricardo Nickenig Vissoci, Fernando Almeida-Val, Daniel Barros de Castro, Wuelton Monteiro, Jacqueline de Almeida Gonçalves Sachett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0013423
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