Initiation of insulin therapy in patients with type 2 diabetes: An observational study
The aim of the study was to assess the initiation of insulin therapy in patients with type 2 diabetes using health claims data on prescription medicines. The study evaluated time to insulin initiation and prescribing patterns of other anti-diabetic medicines before and after insulin initiation. Five...
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| Format: | Article |
| Language: | English |
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Sciendo
2022-03-01
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| Series: | Acta Pharmaceutica |
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| Online Access: | https://doi.org/10.2478/acph-2022-0011 |
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| author | Zerovnik Spela Kos Mitja Locatelli Igor |
| author_facet | Zerovnik Spela Kos Mitja Locatelli Igor |
| author_sort | Zerovnik Spela |
| collection | DOAJ |
| description | The aim of the study was to assess the initiation of insulin therapy in patients with type 2 diabetes using health claims data on prescription medicines. The study evaluated time to insulin initiation and prescribing patterns of other anti-diabetic medicines before and after insulin initiation. Five years after starting non-insulin antidiabetic therapy, 6.4 % of patients were prescribed insulin, which is substantially lower compared to other similar studies. Among all patients who initiated insulin therapy in 2013, 30 % did not continue any other antidiabetic therapy. However, this proportion was lowered to 20 % in 2018. Before insulin initiation in 2018, metformin was prescribed in only 67 % of patients and sulfonylureas in 78 % of patients. Moreover, metformin and sulfonylureas were discontinued after insulin initiation in 26 and 37 % of patients, resp. More attention should be paid to the continuation of oral anti-diabetics, particularly metformin, after insulin initiation. |
| format | Article |
| id | doaj-art-ce22215ee3764e55a54647068ab6c06f |
| institution | Kabale University |
| issn | 1846-9558 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Pharmaceutica |
| spelling | doaj-art-ce22215ee3764e55a54647068ab6c06f2025-02-02T02:10:55ZengSciendoActa Pharmaceutica1846-95582022-03-0172114715710.2478/acph-2022-0011Initiation of insulin therapy in patients with type 2 diabetes: An observational studyZerovnik Spela0Kos Mitja1Locatelli Igor2University of Ljubljana, Faculty of Pharmacy Ljubljana, SloveniaUniversity of Ljubljana, Faculty of Pharmacy Ljubljana, SloveniaUniversity of Ljubljana, Faculty of Pharmacy Ljubljana, SloveniaThe aim of the study was to assess the initiation of insulin therapy in patients with type 2 diabetes using health claims data on prescription medicines. The study evaluated time to insulin initiation and prescribing patterns of other anti-diabetic medicines before and after insulin initiation. Five years after starting non-insulin antidiabetic therapy, 6.4 % of patients were prescribed insulin, which is substantially lower compared to other similar studies. Among all patients who initiated insulin therapy in 2013, 30 % did not continue any other antidiabetic therapy. However, this proportion was lowered to 20 % in 2018. Before insulin initiation in 2018, metformin was prescribed in only 67 % of patients and sulfonylureas in 78 % of patients. Moreover, metformin and sulfonylureas were discontinued after insulin initiation in 26 and 37 % of patients, resp. More attention should be paid to the continuation of oral anti-diabetics, particularly metformin, after insulin initiation.https://doi.org/10.2478/acph-2022-0011diabetes mellitusinsulinmetforminsulfonylurea |
| spellingShingle | Zerovnik Spela Kos Mitja Locatelli Igor Initiation of insulin therapy in patients with type 2 diabetes: An observational study Acta Pharmaceutica diabetes mellitus insulin metformin sulfonylurea |
| title | Initiation of insulin therapy in patients with type 2 diabetes: An observational study |
| title_full | Initiation of insulin therapy in patients with type 2 diabetes: An observational study |
| title_fullStr | Initiation of insulin therapy in patients with type 2 diabetes: An observational study |
| title_full_unstemmed | Initiation of insulin therapy in patients with type 2 diabetes: An observational study |
| title_short | Initiation of insulin therapy in patients with type 2 diabetes: An observational study |
| title_sort | initiation of insulin therapy in patients with type 2 diabetes an observational study |
| topic | diabetes mellitus insulin metformin sulfonylurea |
| url | https://doi.org/10.2478/acph-2022-0011 |
| work_keys_str_mv | AT zerovnikspela initiationofinsulintherapyinpatientswithtype2diabetesanobservationalstudy AT kosmitja initiationofinsulintherapyinpatientswithtype2diabetesanobservationalstudy AT locatelliigor initiationofinsulintherapyinpatientswithtype2diabetesanobservationalstudy |