Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa [version 2; peer review: 2 approved, 1 approved with reservations]

Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa [version 2; peer review: 2 approved, 1 approved with reservations]

Background There is limited knowledge regarding African genetic drivers of disease due to prohibitive costs of large-scale genomic research in Africa. Methods We piloted a scalable virtual genotyped cohort in South Africa that was affordable in this resource-limited context, cost-effective, scalable...

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Bibliographic Details
Main Authors: Robert J Wilkinson, Francisco Lakay, Nicki Tiffin, Joel A Dave, Catherine Riou, Peter Raubenheimer, Anna K Coussens, Tsaone Tamuhla, Melissa J Blumenthal, Maleeka Abrahams
Format: Article
Language:English
Published: Wellcome 2025-01-01
Series:Wellcome Open Research
Subjects:
Electronic routine health data
virtual cohorts
African genetic data
H3Africa Illumina micro-array
genotype data
tiered informed consent
eng
Online Access:https://wellcomeopenresearch.org/articles/9-620/v2
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