StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.

Population genetics focuses on the analysis of genetic differences within and between-group of individuals and the inference of the populations' structure. These analyses are usually carried out using Bayesian clustering or maximum likelihood estimation algorithms that assign individuals to a g...

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Main Authors: Nicola G Criscuolo, Claudia Angelini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0229330&type=printable
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author Nicola G Criscuolo
Claudia Angelini
author_facet Nicola G Criscuolo
Claudia Angelini
author_sort Nicola G Criscuolo
collection DOAJ
description Population genetics focuses on the analysis of genetic differences within and between-group of individuals and the inference of the populations' structure. These analyses are usually carried out using Bayesian clustering or maximum likelihood estimation algorithms that assign individuals to a given population depending on specific genetic patterns. Although several tools were developed to perform population genetics analysis, their standard graphical outputs may not be sufficiently informative for users lacking interactivity and complete information. StructuRly aims to resolve this problem by offering a complete environment for population analysis. In particular, StructuRly combines the statistical power of the R language with the friendly interfaces implemented using the shiny libraries to provide a novel tool for performing population clustering, evaluating several genetic indexes, and comparing results. Moreover, graphical representations are interactive and can be easily personalized. StructuRly is available either as R package on GitHub, with detailed information for its installation and use and as shinyapps.io servers for those users who are not familiar with R and the RStudio IDE. The application has been tested on Linux, macOS and Windows operative systems and can be launched as a shiny app in every web browser.
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spelling doaj-art-ce12e07b98ca4ddf9b7afdf6904f40412025-08-20T03:32:20ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01152e022933010.1371/journal.pone.0229330StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.Nicola G CriscuoloClaudia AngeliniPopulation genetics focuses on the analysis of genetic differences within and between-group of individuals and the inference of the populations' structure. These analyses are usually carried out using Bayesian clustering or maximum likelihood estimation algorithms that assign individuals to a given population depending on specific genetic patterns. Although several tools were developed to perform population genetics analysis, their standard graphical outputs may not be sufficiently informative for users lacking interactivity and complete information. StructuRly aims to resolve this problem by offering a complete environment for population analysis. In particular, StructuRly combines the statistical power of the R language with the friendly interfaces implemented using the shiny libraries to provide a novel tool for performing population clustering, evaluating several genetic indexes, and comparing results. Moreover, graphical representations are interactive and can be easily personalized. StructuRly is available either as R package on GitHub, with detailed information for its installation and use and as shinyapps.io servers for those users who are not familiar with R and the RStudio IDE. The application has been tested on Linux, macOS and Windows operative systems and can be launched as a shiny app in every web browser.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0229330&type=printable
spellingShingle Nicola G Criscuolo
Claudia Angelini
StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.
PLoS ONE
title StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.
title_full StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.
title_fullStr StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.
title_full_unstemmed StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.
title_short StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.
title_sort structurly a novel shiny app to produce comprehensive detailed and interactive plots for population genetic analysis
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0229330&type=printable
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