Astaxanthin mediated repair of tBHP-Induced cellular injury in chondrocytes

Astaxanthin mediated repair of tBHP-Induced cellular injury in chondrocytes

Objective This study investigates how astaxanthin (AST) counters tert-butyl hydroperoxide (tBHP)-induced cellular damage in C28/I2 chondrocytes, focusing on the circ-HP1BP3/miR-139-5p/SOD1 signaling pathway and its use in sustained-release microspheres for osteoarthritis treatment.Methods We employe...

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Bibliographic Details
Main Authors: Wenwei Liang, Gang Liu, Weibo Zhou, Wei Chen, Yaojun Lu, Hao Wu, Yao Qin, Chunhui Zhu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Redox Report
Subjects:
Astaxanthin
C28/I2 cells
tBHP
Circ-HP1BP3
Mir-139-5p
SOD1
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2024.2422271
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