Long-term systemic androgen deprivation partially modulates neuroinflammation in male App NL−G−F/NL−G−F mice

Abstract Alzheimer’s disease (AD) is the leading neurodegenerative disease manifesting cognitive impairment. Its procession is regulated by activated glial cell–mediated neuroinflammation. Although estrogen deprivation is a known risk factor for AD in females, the impact of androgen deprivation on A...

Full description

Saved in:
Bibliographic Details
Main Authors: Kasumi Maekawa, Akira Sobue, Okiru Komine, Yuko Saito, Shigeo Murayama, Takaomi C. Saido, Takashi Saito, Koji Yamanaka
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-98825-z
Tags: Add Tag
No Tags, Be the first to tag this record!