Polymorphisms in immunosuppression-related genes are associated with AML

Polymorphisms in immunosuppression-related genes are associated with AML

BackgroundAcute myeloid leukemia (AML) is a hematologic malignancy with poor overall survival (OS). The immunosuppressive microenvironment significantly impacts AML development and chemoresistance. Despite new immunotherapeutic strategies entering standard clinical care for various tumors, progress...

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Bibliographic Details
Main Authors: Mingying Li, Jingjing Ye, Mengyuan Chang, Lei Feng, Tingting Liu, Di Zhang, Yuyan Wu, Yuechan Ma, Guangqiang Meng, Chunyan Ji, Tao Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
AML
immunosuppression-related genes
treatment response
prognosis
SNPs
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1530510/full
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