Therapeutic response to combination of oral isotretinoin and topical 0.1% tacrolimus ointment in lichen planus pigmentosus: A case series
Lichen Planus Pigmentosus (LPP) is a pigmentary disorder of unknown etiology, presenting with diffuse hyperpigmentation in sun-exposed areas. It is a cosmetically distressing pigmentary disorder often posing a therapeutic challenge. There are few reports showing efficacy of oral isotretinoin and top...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-01-01
|
| Series: | Pigment International |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/pigmentinternational_46_21 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849471509018443776 |
|---|---|
| author | Taru Garg Riaz Ahmed Anuja Rao Vibhu Mendiratta |
| author_facet | Taru Garg Riaz Ahmed Anuja Rao Vibhu Mendiratta |
| author_sort | Taru Garg |
| collection | DOAJ |
| description | Lichen Planus Pigmentosus (LPP) is a pigmentary disorder of unknown etiology, presenting with diffuse hyperpigmentation in sun-exposed areas. It is a cosmetically distressing pigmentary disorder often posing a therapeutic challenge. There are few reports showing efficacy of oral isotretinoin and topical tacrolimus in LPP. However combination of both these therapeutic modalities has not been described earlier. Herein we report a series of 10 patients who showed good response to combination of oral isotretinoin (20 mg/day) and topical 0.1% tacrolimus ointment. |
| format | Article |
| id | doaj-art-cdf8c55db0194c6099d4e821daa1cf53 |
| institution | Kabale University |
| issn | 2349-5847 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Pigment International |
| spelling | doaj-art-cdf8c55db0194c6099d4e821daa1cf532025-08-20T03:24:48ZengWolters Kluwer Medknow PublicationsPigment International2349-58472025-01-01121535610.4103/pigmentinternational_46_21Therapeutic response to combination of oral isotretinoin and topical 0.1% tacrolimus ointment in lichen planus pigmentosus: A case seriesTaru GargRiaz AhmedAnuja RaoVibhu MendirattaLichen Planus Pigmentosus (LPP) is a pigmentary disorder of unknown etiology, presenting with diffuse hyperpigmentation in sun-exposed areas. It is a cosmetically distressing pigmentary disorder often posing a therapeutic challenge. There are few reports showing efficacy of oral isotretinoin and topical tacrolimus in LPP. However combination of both these therapeutic modalities has not been described earlier. Herein we report a series of 10 patients who showed good response to combination of oral isotretinoin (20 mg/day) and topical 0.1% tacrolimus ointment.https://journals.lww.com/10.4103/pigmentinternational_46_21lichen planus pigmentosus (lpp)oral isotretinointopical tacrolimus |
| spellingShingle | Taru Garg Riaz Ahmed Anuja Rao Vibhu Mendiratta Therapeutic response to combination of oral isotretinoin and topical 0.1% tacrolimus ointment in lichen planus pigmentosus: A case series Pigment International lichen planus pigmentosus (lpp) oral isotretinoin topical tacrolimus |
| title | Therapeutic response to combination of oral isotretinoin and topical 0.1% tacrolimus ointment in lichen planus pigmentosus: A case series |
| title_full | Therapeutic response to combination of oral isotretinoin and topical 0.1% tacrolimus ointment in lichen planus pigmentosus: A case series |
| title_fullStr | Therapeutic response to combination of oral isotretinoin and topical 0.1% tacrolimus ointment in lichen planus pigmentosus: A case series |
| title_full_unstemmed | Therapeutic response to combination of oral isotretinoin and topical 0.1% tacrolimus ointment in lichen planus pigmentosus: A case series |
| title_short | Therapeutic response to combination of oral isotretinoin and topical 0.1% tacrolimus ointment in lichen planus pigmentosus: A case series |
| title_sort | therapeutic response to combination of oral isotretinoin and topical 0 1 tacrolimus ointment in lichen planus pigmentosus a case series |
| topic | lichen planus pigmentosus (lpp) oral isotretinoin topical tacrolimus |
| url | https://journals.lww.com/10.4103/pigmentinternational_46_21 |
| work_keys_str_mv | AT tarugarg therapeuticresponsetocombinationoforalisotretinoinandtopical01tacrolimusointmentinlichenplanuspigmentosusacaseseries AT riazahmed therapeuticresponsetocombinationoforalisotretinoinandtopical01tacrolimusointmentinlichenplanuspigmentosusacaseseries AT anujarao therapeuticresponsetocombinationoforalisotretinoinandtopical01tacrolimusointmentinlichenplanuspigmentosusacaseseries AT vibhumendiratta therapeuticresponsetocombinationoforalisotretinoinandtopical01tacrolimusointmentinlichenplanuspigmentosusacaseseries |