Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in China
Objective Whether sarcopenia is detrimental to depression is still controversial, which may be due to the three components of the sarcopenia. Our objective was to define the correlation between depression and sarcopenia in older Chinese community dwellers.Design The study has a cross-sectional desig...
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BMJ Publishing Group
2020-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/10/9/e038089.full |
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| author | Lei Chen Yunlu Sheng Hanmei Qi Tingting Tang Jing Yu Shan Lv |
| author_facet | Lei Chen Yunlu Sheng Hanmei Qi Tingting Tang Jing Yu Shan Lv |
| author_sort | Lei Chen |
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| description | Objective Whether sarcopenia is detrimental to depression is still controversial, which may be due to the three components of the sarcopenia. Our objective was to define the correlation between depression and sarcopenia in older Chinese community dwellers.Design The study has a cross-sectional design.Setting The study was conducted in Jiangsu, China.Participants A total of 101 men and 149 women aged 60 years or older were recruited.Outcome measures Lean tissue mass was measured by dual-energy X-ray absorptiometry. Muscle strength in the upper and lower limbs was measured by a handheld dynamometer and a chair stand test, respectively. Physical performance was assessed by gait speed and standing balance tests. Depressive mood was assessed using the Geriatric Depression Scale-30 (range 0–30).Results Participants in the sarcopenia group had a higher mean depression score than the normal group (p=0.002). Pearson’s correlation analysis showed that depression was negatively associated with muscle strength (handgrip strength: R=−0.170, p=0.028 for women, R=−0.196, p=0.048 for men; chair stand test performance: R=0.252, p=0.002 for women, R=0.311, p=0.001 for men) and physical performance (gait speed: R=−0.200, p=0.009, standing balance test performance: R=−0.224, p=0.006, Short Physical Performance Battery (SPPB): R=−0.218, p=0.007 for women; SPPB: R=−0.252, p=0.01 for men). Multiple linear regression models revealed that depressive mood was inversely associated with chair stand test (β=0.325, p<0.001), gait speed (β=−0.009, p=0.041) and standing balance test (β=−0.24, p=0.016) after adjusting for confounding factors, while no significant correlation was observed between depressive mood and muscle mass.Conclusion The diagnostic components of sarcopenia—strength of the leg muscles (chair stand test) and physical performance (gait speed and standing balance test)—were associated with depressive mood. |
| format | Article |
| id | doaj-art-cdf25a4c18474da39303c8d70d1e0f5b |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2020-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-cdf25a4c18474da39303c8d70d1e0f5b2025-01-08T19:40:09ZengBMJ Publishing GroupBMJ Open2044-60552020-09-0110910.1136/bmjopen-2020-038089Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in ChinaLei Chen0Yunlu Sheng1Hanmei Qi2Tingting Tang3Jing Yu4Shan Lv51 Bio-X Institutes, Key Laboratory for the Genetics of Development and Neuropsychiatric Disorders (Ministry of Education), Brain Health and Brain Technology Center at Global Institute of Future Technology, Institute of Psychology and Behavioral Science, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Geratology, the First Hospital Affiliated to Nanjing Medical University, Nanjing, ChinaDepartment of Geratology, the First Hospital Affiliated to Nanjing Medical University, Nanjing, ChinaDepartment of Geratology, The First People`s Hospital of Yancheng, Yancheng, ChinaDepartment of Geratology, the First Hospital Affiliated to Nanjing Medical University, Nanjing, ChinaDepartment of Geratology, the First Hospital Affiliated to Nanjing Medical University, Nanjing, ChinaObjective Whether sarcopenia is detrimental to depression is still controversial, which may be due to the three components of the sarcopenia. Our objective was to define the correlation between depression and sarcopenia in older Chinese community dwellers.Design The study has a cross-sectional design.Setting The study was conducted in Jiangsu, China.Participants A total of 101 men and 149 women aged 60 years or older were recruited.Outcome measures Lean tissue mass was measured by dual-energy X-ray absorptiometry. Muscle strength in the upper and lower limbs was measured by a handheld dynamometer and a chair stand test, respectively. Physical performance was assessed by gait speed and standing balance tests. Depressive mood was assessed using the Geriatric Depression Scale-30 (range 0–30).Results Participants in the sarcopenia group had a higher mean depression score than the normal group (p=0.002). Pearson’s correlation analysis showed that depression was negatively associated with muscle strength (handgrip strength: R=−0.170, p=0.028 for women, R=−0.196, p=0.048 for men; chair stand test performance: R=0.252, p=0.002 for women, R=0.311, p=0.001 for men) and physical performance (gait speed: R=−0.200, p=0.009, standing balance test performance: R=−0.224, p=0.006, Short Physical Performance Battery (SPPB): R=−0.218, p=0.007 for women; SPPB: R=−0.252, p=0.01 for men). Multiple linear regression models revealed that depressive mood was inversely associated with chair stand test (β=0.325, p<0.001), gait speed (β=−0.009, p=0.041) and standing balance test (β=−0.24, p=0.016) after adjusting for confounding factors, while no significant correlation was observed between depressive mood and muscle mass.Conclusion The diagnostic components of sarcopenia—strength of the leg muscles (chair stand test) and physical performance (gait speed and standing balance test)—were associated with depressive mood.https://bmjopen.bmj.com/content/10/9/e038089.full |
| spellingShingle | Lei Chen Yunlu Sheng Hanmei Qi Tingting Tang Jing Yu Shan Lv Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in China BMJ Open |
| title | Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in China |
| title_full | Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in China |
| title_fullStr | Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in China |
| title_full_unstemmed | Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in China |
| title_short | Correlation of sarcopenia and depressive mood in older community dwellers: a cross-sectional observational study in China |
| title_sort | correlation of sarcopenia and depressive mood in older community dwellers a cross sectional observational study in china |
| url | https://bmjopen.bmj.com/content/10/9/e038089.full |
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