Imaging Features in Pancreatic Neuroendocrine Tumor with Intraductal Growth and Venous Invasion: A Case Report and Literature Review
Pancreatic neuroendocrine tumors (PanNETs) are a rare type of pancreatic neoplasm. Pan- NETs with intraductal growth are considered extremely rare, and ductal involvement in NETs has been reported to correlate with aggressive clinical behavior. A 67-year-old male was referred to our hospital for...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Radiology
2025-05-01
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| Series: | Journal of the Korean Society of Radiology |
| Subjects: | |
| Online Access: | https://doi.org/10.3348/jksr.2024.0064 |
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| Summary: | Pancreatic neuroendocrine tumors (PanNETs) are a rare type of pancreatic neoplasm. Pan-
NETs with intraductal growth are considered extremely rare, and ductal involvement in
NETs has been reported to correlate with aggressive clinical behavior. A 67-year-old male
was referred to our hospital for further evaluation of a pancreatic tumor. Various imaging
modalities, including ultrasonography, contrast-enhanced CT, MRI, and endoscopic ultrasonography
(EUS), demonstrated a well-defined pancreatic mass in the head and body, primarily
located within the main pancreatic duct with extension to the main portal vein. Histological
diagnosis from an EUS-guided biopsy revealed a grade 3 well-differentiated NET.
The patient was scheduled for surgery; however, multiple additional bone metastases were
identified on 18F-fluorodeoxyglucose PET/CT. Although the presence of intraductal growth
and portal vein invasion is uncommon in PanNETs, aggressive workup and treatment are
essential in such cases. |
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| ISSN: | 2951-0805 |