IgG4-related lung disease with pulmonary lesions and recurrent pleural effusion: A case of report
We report a rare case of IgG4-related lung disease (RLD) with pulmonary lesions and recurrent pleural effusion to improve the diagnosis and treatment of this disease. A 60-year-old man was admitted to hospital for cough and dyspnea. CT scan showed a right lower lobe intrapulmonary mass with unilater...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-08-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325003279 |
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| author | Ning Xia Wei Wang Wei Zhang Yan Li Xiu-Hong Nie |
| author_facet | Ning Xia Wei Wang Wei Zhang Yan Li Xiu-Hong Nie |
| author_sort | Ning Xia |
| collection | DOAJ |
| description | We report a rare case of IgG4-related lung disease (RLD) with pulmonary lesions and recurrent pleural effusion to improve the diagnosis and treatment of this disease. A 60-year-old man was admitted to hospital for cough and dyspnea. CT scan showed a right lower lobe intrapulmonary mass with unilateral right-sided pleural effusion. Histology revealed no malignant findings. After 1 year, the patient re-admitted to our hospital with high serum level of IgG4 and IgE concentrations. CT scan demonstrated partial resolution of intrapulmonary mass and right-sided pleural effusion, while concurrently revealing interval development of substantial left-sided pleural effusion. The patient was diagnosed with IgG4-RLD by biopsy finally. This is a first case report of IgG4-RLD with intrapulmonary lesions accompanied by asynchronous, rapidly accumulating bilateral pleural effusions. Clinicians should consider the possibility of IgG4-RLD with intrapulmonary lesions accompanied by asynchronous, rapidly growing bilateral pleural effusion, particularly after rigorously excluding common diseases. |
| format | Article |
| id | doaj-art-cddfd60d4ec546078749770bb91b9934 |
| institution | OA Journals |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-cddfd60d4ec546078749770bb91b99342025-08-20T02:05:09ZengElsevierRadiology Case Reports1930-04332025-08-012083820382510.1016/j.radcr.2025.04.028IgG4-related lung disease with pulmonary lesions and recurrent pleural effusion: A case of reportNing Xia0Wei Wang1Wei Zhang2Yan Li3Xiu-Hong Nie4Department of Respiratory Disease, Xuanwu Hospital, Capital Medical University, Beijing, PR ChinaDepartment of Pathology, Xuanwu Hospital, Capital Medical University, Beijing, PR ChinaDepartment of Respiratory Disease, Xuanwu Hospital, Capital Medical University, Beijing, PR ChinaDepartment of Respiratory Disease, Xuanwu Hospital, Capital Medical University, Beijing, PR ChinaDepartment of Respiratory Disease, Xuanwu Hospital, Capital Medical University, Beijing, PR China; Corresponding author.We report a rare case of IgG4-related lung disease (RLD) with pulmonary lesions and recurrent pleural effusion to improve the diagnosis and treatment of this disease. A 60-year-old man was admitted to hospital for cough and dyspnea. CT scan showed a right lower lobe intrapulmonary mass with unilateral right-sided pleural effusion. Histology revealed no malignant findings. After 1 year, the patient re-admitted to our hospital with high serum level of IgG4 and IgE concentrations. CT scan demonstrated partial resolution of intrapulmonary mass and right-sided pleural effusion, while concurrently revealing interval development of substantial left-sided pleural effusion. The patient was diagnosed with IgG4-RLD by biopsy finally. This is a first case report of IgG4-RLD with intrapulmonary lesions accompanied by asynchronous, rapidly accumulating bilateral pleural effusions. Clinicians should consider the possibility of IgG4-RLD with intrapulmonary lesions accompanied by asynchronous, rapidly growing bilateral pleural effusion, particularly after rigorously excluding common diseases.http://www.sciencedirect.com/science/article/pii/S1930043325003279IgG4-related lung diseaseRecurrent pleural effusionPulmonary lesions |
| spellingShingle | Ning Xia Wei Wang Wei Zhang Yan Li Xiu-Hong Nie IgG4-related lung disease with pulmonary lesions and recurrent pleural effusion: A case of report Radiology Case Reports IgG4-related lung disease Recurrent pleural effusion Pulmonary lesions |
| title | IgG4-related lung disease with pulmonary lesions and recurrent pleural effusion: A case of report |
| title_full | IgG4-related lung disease with pulmonary lesions and recurrent pleural effusion: A case of report |
| title_fullStr | IgG4-related lung disease with pulmonary lesions and recurrent pleural effusion: A case of report |
| title_full_unstemmed | IgG4-related lung disease with pulmonary lesions and recurrent pleural effusion: A case of report |
| title_short | IgG4-related lung disease with pulmonary lesions and recurrent pleural effusion: A case of report |
| title_sort | igg4 related lung disease with pulmonary lesions and recurrent pleural effusion a case of report |
| topic | IgG4-related lung disease Recurrent pleural effusion Pulmonary lesions |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325003279 |
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