Exposure to ambient air pollution over developmental stages induced neurodevelopmental impairment in mice offspring via microbiome-gut-brain axis

Exposure to ambient air pollution over developmental stages induced neurodevelopmental impairment in mice offspring via microbiome-gut-brain axis

Abstract Exposure to air pollution has been increasingly recognized as a risk factor for neurodevelopmental disorders, and gut microbiome may play a critical role. However, current evidence still remains scarce. In the present study, mice were exposed to real-time ambient air pollution from concepti...

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Main Authors: Zijun Yang, Yi Zhang, Shanshan Ran, Jingyi Zhang, Yonggui Gao, Yali Zhang, Xinyue Li, Baozhuo Ai, Shengtao Wei, Fei Tian, Guang Jia, Hualiang Lin, Zhangjian Chen, Zilong Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Particle and Fibre Toxicology
Subjects:
PM2.5
Real-time exposure
Early-life
Developmental stages
Neurodevelopmental impairment
Behavioral experiment
Online Access:https://doi.org/10.1186/s12989-025-00637-6
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https://doi.org/10.1186/s12989-025-00637-6

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