Modern Recent on the Laboratory Diagnosis of Clostridium Difficile-associated Infection

In the review the current information on the laboratory diagnosis of Clostridium difficile-associated infection. Made a critical assessment of the effectiveness and specificity of the modern methods of diagnosis: methods of isolation and identification of Clostridium difficile cultures by studying t...

Full description

Saved in:
Bibliographic Details
Main Authors: A. S. Kvet naya, P. S. Makridi, M. K. Behtereva
Format: Article
Language:Russian
Published: Journal Infectology 2014-09-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/180
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849241594921746432
author A. S. Kvet naya,
P. S. Makridi
M. K. Behtereva
author_facet A. S. Kvet naya,
P. S. Makridi
M. K. Behtereva
author_sort A. S. Kvet naya,
collection DOAJ
description In the review the current information on the laboratory diagnosis of Clostridium difficile-associated infection. Made a critical assessment of the effectiveness and specificity of the modern methods of diagnosis: methods of isolation and identification of Clostridium difficile cultures by studying the biochemical characteristics, the use of test kits – API 20A and Rapid Ana II-tests, determination of protein spectra by means of MALDI-TOF mass spectrometry. Describes how to display toxigenic strains of Clostridium difficile based on Dot-immunoblotting, PCR, and immunochromatography, as well as methods for determining the toxin Clostridium difficile in stool samples by determining the cytotoxic effect of toxins on tissue culture, latex agglutination test, ELISA and enzyme-linked fluorescent assay.
format Article
id doaj-art-cddcdd0cea644e7ba5dcdfc466110ac9
institution Kabale University
issn 2072-6732
language Russian
publishDate 2014-09-01
publisher Journal Infectology
record_format Article
series Журнал инфектологии
spelling doaj-art-cddcdd0cea644e7ba5dcdfc466110ac92025-08-20T04:00:07ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-015351210.22625/2072-6732-2013-5-3-5-12194Modern Recent on the Laboratory Diagnosis of Clostridium Difficile-associated InfectionA. S. Kvet naya,0P. S. Makridi1M. K. Behtereva2Scince Research Institute of Children’s Infection of FMBA of Russia , Saint-PetersburgScince Research Institute of Children’s Infection of FMBA of Russia , Saint-PetersburgScince Research Institute of Children’s Infection of FMBA of Russia , Saint-PetersburgIn the review the current information on the laboratory diagnosis of Clostridium difficile-associated infection. Made a critical assessment of the effectiveness and specificity of the modern methods of diagnosis: methods of isolation and identification of Clostridium difficile cultures by studying the biochemical characteristics, the use of test kits – API 20A and Rapid Ana II-tests, determination of protein spectra by means of MALDI-TOF mass spectrometry. Describes how to display toxigenic strains of Clostridium difficile based on Dot-immunoblotting, PCR, and immunochromatography, as well as methods for determining the toxin Clostridium difficile in stool samples by determining the cytotoxic effect of toxins on tissue culture, latex agglutination test, ELISA and enzyme-linked fluorescent assay.https://journal.niidi.ru/jofin/article/view/180clostridium difficileclostridium difficile – associated diseasetoxinslaboratory diagnostics
spellingShingle A. S. Kvet naya,
P. S. Makridi
M. K. Behtereva
Modern Recent on the Laboratory Diagnosis of Clostridium Difficile-associated Infection
Журнал инфектологии
clostridium difficile
clostridium difficile – associated disease
toxins
laboratory diagnostics
title Modern Recent on the Laboratory Diagnosis of Clostridium Difficile-associated Infection
title_full Modern Recent on the Laboratory Diagnosis of Clostridium Difficile-associated Infection
title_fullStr Modern Recent on the Laboratory Diagnosis of Clostridium Difficile-associated Infection
title_full_unstemmed Modern Recent on the Laboratory Diagnosis of Clostridium Difficile-associated Infection
title_short Modern Recent on the Laboratory Diagnosis of Clostridium Difficile-associated Infection
title_sort modern recent on the laboratory diagnosis of clostridium difficile associated infection
topic clostridium difficile
clostridium difficile – associated disease
toxins
laboratory diagnostics
url https://journal.niidi.ru/jofin/article/view/180
work_keys_str_mv AT askvetnaya modernrecentonthelaboratorydiagnosisofclostridiumdifficileassociatedinfection
AT psmakridi modernrecentonthelaboratorydiagnosisofclostridiumdifficileassociatedinfection
AT mkbehtereva modernrecentonthelaboratorydiagnosisofclostridiumdifficileassociatedinfection