Supersaturated Gel Formulation (SGF) of Atorvastatin at a Maximum Dose of 80 mg with Enhanced Solubility, Dissolution, and Physical Stability

Supersaturated Gel Formulation (SGF) of Atorvastatin at a Maximum Dose of 80 mg with Enhanced Solubility, Dissolution, and Physical Stability

The objective of this work was to develop a supersaturated gel formulation (SGF) loaded with the maximum atorvastatin calcium trihydrate (ATR) dose. The maximum dose strength of ATR needs to be reduced through improving solubility and dissolution rate to mitigate side effects due to the necessity of...

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Bibliographic Details
Main Authors: Jin Woo Park, Sa-Won Lee, Jun Hak Lee, Sung Mo Park, Sung Jun Cho, Han-Joo Maeng, Kwan Hyung Cho
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Gels
Subjects:
atorvastatin calcium
organogel formulation
dissolution
solubility
physical stability
Online Access:https://www.mdpi.com/2310-2861/10/12/837
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