Intraductal papilloma of minor salivary gland: a case report and literature review

Intraductal papilloma is a rare benign neoplasm arising from the secretory ducts of the salivary glands. A 79-year-old man with an intraductal papilloma located in the minor salivary gland of sublingual mucosa was reported. The lesion, characterized by extensive internal papillomatous hyperplasia, w...

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Main Authors: Yifei Wang, Xiaowei Li, Chunfang Yao, Yi Wu, Hengli Ni
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Oral Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/froh.2025.1508614/full
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author Yifei Wang
Xiaowei Li
Chunfang Yao
Yi Wu
Hengli Ni
author_facet Yifei Wang
Xiaowei Li
Chunfang Yao
Yi Wu
Hengli Ni
author_sort Yifei Wang
collection DOAJ
description Intraductal papilloma is a rare benign neoplasm arising from the secretory ducts of the salivary glands. A 79-year-old man with an intraductal papilloma located in the minor salivary gland of sublingual mucosa was reported. The lesion, characterized by extensive internal papillomatous hyperplasia, was confirmed through histopathology and immunohistochemistry. We conducted a literature review to clarify intraductal papilloma and differences between inverted ductal papilloma, highlighting the significance of CK7 and MUC-1 immunohistochemical staining in diagnosing intraductal papilloma.
format Article
id doaj-art-cdd267b918cb4c4f942e209e5ac89560
institution Kabale University
issn 2673-4842
language English
publishDate 2025-02-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oral Health
spelling doaj-art-cdd267b918cb4c4f942e209e5ac895602025-02-12T07:26:31ZengFrontiers Media S.A.Frontiers in Oral Health2673-48422025-02-01610.3389/froh.2025.15086141508614Intraductal papilloma of minor salivary gland: a case report and literature reviewYifei WangXiaowei LiChunfang YaoYi WuHengli NiIntraductal papilloma is a rare benign neoplasm arising from the secretory ducts of the salivary glands. A 79-year-old man with an intraductal papilloma located in the minor salivary gland of sublingual mucosa was reported. The lesion, characterized by extensive internal papillomatous hyperplasia, was confirmed through histopathology and immunohistochemistry. We conducted a literature review to clarify intraductal papilloma and differences between inverted ductal papilloma, highlighting the significance of CK7 and MUC-1 immunohistochemical staining in diagnosing intraductal papilloma.https://www.frontiersin.org/articles/10.3389/froh.2025.1508614/fullintraductal papillomainverted ductal papillomaductal papillomacystadenomaminor salivary gland
spellingShingle Yifei Wang
Xiaowei Li
Chunfang Yao
Yi Wu
Hengli Ni
Intraductal papilloma of minor salivary gland: a case report and literature review
Frontiers in Oral Health
intraductal papilloma
inverted ductal papilloma
ductal papilloma
cystadenoma
minor salivary gland
title Intraductal papilloma of minor salivary gland: a case report and literature review
title_full Intraductal papilloma of minor salivary gland: a case report and literature review
title_fullStr Intraductal papilloma of minor salivary gland: a case report and literature review
title_full_unstemmed Intraductal papilloma of minor salivary gland: a case report and literature review
title_short Intraductal papilloma of minor salivary gland: a case report and literature review
title_sort intraductal papilloma of minor salivary gland a case report and literature review
topic intraductal papilloma
inverted ductal papilloma
ductal papilloma
cystadenoma
minor salivary gland
url https://www.frontiersin.org/articles/10.3389/froh.2025.1508614/full
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AT chunfangyao intraductalpapillomaofminorsalivaryglandacasereportandliteraturereview
AT yiwu intraductalpapillomaofminorsalivaryglandacasereportandliteraturereview
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