Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options

The aim of review. To analyse of publications on qualitative and quantitative changes in pattern of intestinal microflora in patients with irritable bowel syndrome (IBS) and options of its treatment by pre-, pro-, and symbiotic drugs.Key points. In the last years more and more data appear on changes...

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Main Authors: Ye. A. Poluektova, S. Yu. Kuchumova, O. S. Shifrin, A. A. Sheptulin, V. T. Ivashkin
Format: Article
Language:Russian
Published: Gastro LLC 2014-09-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/1119
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author Ye. A. Poluektova
S. Yu. Kuchumova
O. S. Shifrin
A. A. Sheptulin
V. T. Ivashkin
author_facet Ye. A. Poluektova
S. Yu. Kuchumova
O. S. Shifrin
A. A. Sheptulin
V. T. Ivashkin
author_sort Ye. A. Poluektova
collection DOAJ
description The aim of review. To analyse of publications on qualitative and quantitative changes in pattern of intestinal microflora in patients with irritable bowel syndrome (IBS) and options of its treatment by pre-, pro-, and symbiotic drugs.Key points. In the last years more and more data appear on changes in qualitative and quantitative spectrum of intestinal microflora in combination to low degree inflammation of colonic mucosa at IBS that allowed to reconsider standard concepts on pathogenesis of this functional disorder. Agents restoring intestinal microflora balance are effective for symptom relief of this disease.Conclusion. The analysis of the information concerning disorder of qualitative and quantitative structure of intestinal microflora at IBS, mechanisms of action of pre-, pro- and synbiotics, allows to expand essentially treatment options of this disease.
format Article
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institution Kabale University
issn 1382-4376
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language Russian
publishDate 2014-09-01
publisher Gastro LLC
record_format Article
series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-cdcb93cbf78d4cdfa68849d1618d003a2025-02-10T16:14:39ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732014-09-012438997719Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment optionsYe. A. Poluektova0S. Yu. Kuchumova1O. S. Shifrin2A. A. Sheptulin3V. T. Ivashkin4State educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Healthcare of RussiaState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Healthcare of RussiaState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Healthcare of RussiaState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Healthcare of RussiaState educational government-financed institution of higher professional education «Sechenov First Moscow state medical university» Ministry of Healthcare of RussiaThe aim of review. To analyse of publications on qualitative and quantitative changes in pattern of intestinal microflora in patients with irritable bowel syndrome (IBS) and options of its treatment by pre-, pro-, and symbiotic drugs.Key points. In the last years more and more data appear on changes in qualitative and quantitative spectrum of intestinal microflora in combination to low degree inflammation of colonic mucosa at IBS that allowed to reconsider standard concepts on pathogenesis of this functional disorder. Agents restoring intestinal microflora balance are effective for symptom relief of this disease.Conclusion. The analysis of the information concerning disorder of qualitative and quantitative structure of intestinal microflora at IBS, mechanisms of action of pre-, pro- and synbiotics, allows to expand essentially treatment options of this disease.https://www.gastro-j.ru/jour/article/view/1119irritable bowel syndromepathogenesisimbalance of intestinal microfloraprobioticsprebioticssynbiotics
spellingShingle Ye. A. Poluektova
S. Yu. Kuchumova
O. S. Shifrin
A. A. Sheptulin
V. T. Ivashkin
Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
irritable bowel syndrome
pathogenesis
imbalance of intestinal microflora
probiotics
prebiotics
synbiotics
title Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options
title_full Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options
title_fullStr Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options
title_full_unstemmed Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options
title_short Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options
title_sort pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options
topic irritable bowel syndrome
pathogenesis
imbalance of intestinal microflora
probiotics
prebiotics
synbiotics
url https://www.gastro-j.ru/jour/article/view/1119
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AT syukuchumova pathogenicroleofintestinalmicroflorachangesinpatientswithirritablebowelsyndromeandtreatmentoptions
AT osshifrin pathogenicroleofintestinalmicroflorachangesinpatientswithirritablebowelsyndromeandtreatmentoptions
AT aasheptulin pathogenicroleofintestinalmicroflorachangesinpatientswithirritablebowelsyndromeandtreatmentoptions
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