Thermodynamic investigations on host/guest complexation in deep eutectic solvent/water mixtures
The development of formulations based on cyclodextrins (CDs) and deep eutectic solvents (DESs), is an interesting approach to expand the applications of host–guest chemistry. However, there is a lack of information in the literature on the complexation mechanism in these non-conventional media. The...
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Académie des sciences
2024-04-01
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| Series: | Comptes Rendus. Chimie |
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| Online Access: | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.304/ |
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| author | Nakhle, Lamia Kfoury, Miriana Fourmentin, Sophie Greige-Gerges, Hélène Landy, David |
| author_facet | Nakhle, Lamia Kfoury, Miriana Fourmentin, Sophie Greige-Gerges, Hélène Landy, David |
| author_sort | Nakhle, Lamia |
| collection | DOAJ |
| description | The development of formulations based on cyclodextrins (CDs) and deep eutectic solvents (DESs), is an interesting approach to expand the applications of host–guest chemistry. However, there is a lack of information in the literature on the complexation mechanism in these non-conventional media. The aim of this study is to provide, for the first time, fundamental information on the influence of the type and the wt% (weight percent) content of DES in the mixture on the thermodynamic properties (binding strength and complexation mechanism) of a model inclusion complex, β-CD/adamantanol by means of isothermal titration calorimetry (ITC). |
| format | Article |
| id | doaj-art-cdbbfadb6e784bc0a400636ec6b0231b |
| institution | Kabale University |
| issn | 1878-1543 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Académie des sciences |
| record_format | Article |
| series | Comptes Rendus. Chimie |
| spelling | doaj-art-cdbbfadb6e784bc0a400636ec6b0231b2025-02-07T13:41:22ZengAcadémie des sciencesComptes Rendus. Chimie1878-15432024-04-011910.5802/crchim.30410.5802/crchim.304Thermodynamic investigations on host/guest complexation in deep eutectic solvent/water mixturesNakhle, Lamia0Kfoury, Miriana1https://orcid.org/0000-0003-3436-6943Fourmentin, Sophie2https://orcid.org/0000-0002-4334-0051Greige-Gerges, Hélène3https://orcid.org/0000-0003-2134-9423Landy, David4https://orcid.org/0000-0001-6297-6162Bioactive Molecules Research Laboratory, Faculty of Sciences, Lebanese University, 90656 Jdeidet el-Metn, Lebanon; Univ. Littoral Côte d’Opale, UR 4492, UCEIV, Unité de Chimie Environnementale et Interactions sur le Vivant, 59140 Dunkerque, FranceUniv. Littoral Côte d’Opale, UR 4492, UCEIV, Unité de Chimie Environnementale et Interactions sur le Vivant, 59140 Dunkerque, FranceUniv. Littoral Côte d’Opale, UR 4492, UCEIV, Unité de Chimie Environnementale et Interactions sur le Vivant, 59140 Dunkerque, FranceBioactive Molecules Research Laboratory, Faculty of Sciences, Lebanese University, 90656 Jdeidet el-Metn, LebanonUniv. Littoral Côte d’Opale, UR 4492, UCEIV, Unité de Chimie Environnementale et Interactions sur le Vivant, 59140 Dunkerque, FranceThe development of formulations based on cyclodextrins (CDs) and deep eutectic solvents (DESs), is an interesting approach to expand the applications of host–guest chemistry. However, there is a lack of information in the literature on the complexation mechanism in these non-conventional media. The aim of this study is to provide, for the first time, fundamental information on the influence of the type and the wt% (weight percent) content of DES in the mixture on the thermodynamic properties (binding strength and complexation mechanism) of a model inclusion complex, β-CD/adamantanol by means of isothermal titration calorimetry (ITC).https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.304/AdamantanolCyclodextrinsDeep eutectic solventsInclusion thermodynamicsIsothermal titration calorimetry |
| spellingShingle | Nakhle, Lamia Kfoury, Miriana Fourmentin, Sophie Greige-Gerges, Hélène Landy, David Thermodynamic investigations on host/guest complexation in deep eutectic solvent/water mixtures Comptes Rendus. Chimie Adamantanol Cyclodextrins Deep eutectic solvents Inclusion thermodynamics Isothermal titration calorimetry |
| title | Thermodynamic investigations on host/guest complexation in deep eutectic solvent/water mixtures |
| title_full | Thermodynamic investigations on host/guest complexation in deep eutectic solvent/water mixtures |
| title_fullStr | Thermodynamic investigations on host/guest complexation in deep eutectic solvent/water mixtures |
| title_full_unstemmed | Thermodynamic investigations on host/guest complexation in deep eutectic solvent/water mixtures |
| title_short | Thermodynamic investigations on host/guest complexation in deep eutectic solvent/water mixtures |
| title_sort | thermodynamic investigations on host guest complexation in deep eutectic solvent water mixtures |
| topic | Adamantanol Cyclodextrins Deep eutectic solvents Inclusion thermodynamics Isothermal titration calorimetry |
| url | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.304/ |
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