Comparative effects of cantharidin and endothall on gene expression and activity of antioxidant enzymes in Cichorium intybus L.

Cantharidin and its analog, endothall, are known to have phytotoxic effects and their mechanism of action involves the inhibition of phosphatases. Enzymes and antioxidant compounds act as barriers against phytotoxic compounds. Catalase and peroxidase are among the most important antioxidant enzymes....

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Main Authors: Yalda GHOTBZADEH KERMANI, Ramazan Ali KHAVARI NEJAD, Homa MAHMOODZADEH, Khadijeh SHAHROKH ABADI
Format: Article
Language:English
Published: University of Ljubljana Press (Založba Univerze v Ljubljani) 2020-09-01
Series:Acta Agriculturae Slovenica
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Online Access:https://journals.uni-lj.si/aas/article/view/12916
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author Yalda GHOTBZADEH KERMANI
Ramazan Ali KHAVARI NEJAD
Homa MAHMOODZADEH
Khadijeh SHAHROKH ABADI
author_facet Yalda GHOTBZADEH KERMANI
Ramazan Ali KHAVARI NEJAD
Homa MAHMOODZADEH
Khadijeh SHAHROKH ABADI
author_sort Yalda GHOTBZADEH KERMANI
collection DOAJ
description Cantharidin and its analog, endothall, are known to have phytotoxic effects and their mechanism of action involves the inhibition of phosphatases. Enzymes and antioxidant compounds act as barriers against phytotoxic compounds. Catalase and peroxidase are among the most important antioxidant enzymes. Cichorium intybus L. has traditionally been used for its medicinal properties and contains various phytochemical and enzymatic compounds. The present study aimed to investigate the comparative effects of cantharidin and endothall with concentration of 2.5, 5.5 and 10 µg ml-1 on the changes in the gene expression of catalase and glutathione peroxidase. Furthermore, we assess the activities of these enzymes in the shoots and roots of Cichorium intybus L.. According to the findings, the expression of catalase and glutathione peroxidase increased in the samples treated with cantharidin more than endothall compared to the controls in both shoot (the most significant is in cantharidin with 2.5 µg ml-1 concentration) and root samples (the most significant is in cantharidin with 5.5 µg ml-1  concentration). In addition, the activity of catalase and concentrations of cantharidin (2.5 µg ml-1) in shoot samples led to the more intense stimulation of catalase and glutathione peroxidase compared to root samples. We suggest that cantharidin and endothall have negative effect on expression and absorption of antioxidant enzymes.
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spelling doaj-art-cdb61e62d92b4dcaa1969f98567caddc2025-08-20T02:52:56ZengUniversity of Ljubljana Press (Založba Univerze v Ljubljani)Acta Agriculturae Slovenica1854-19412020-09-01116118919710.14720/aas.2020.116.1.123219308Comparative effects of cantharidin and endothall on gene expression and activity of antioxidant enzymes in Cichorium intybus L.Yalda GHOTBZADEH KERMANI0Ramazan Ali KHAVARI NEJAD1Homa MAHMOODZADEH2Khadijeh SHAHROKH ABADI3Science and Research University Of Tehran,Iran.Science and Research University Of Tehran,Iran.Mashhad branch, Islamic Azad University , Mashhad , Iran.Mashhad branch, Islamic Azad University , Mashhad , Iran.Cantharidin and its analog, endothall, are known to have phytotoxic effects and their mechanism of action involves the inhibition of phosphatases. Enzymes and antioxidant compounds act as barriers against phytotoxic compounds. Catalase and peroxidase are among the most important antioxidant enzymes. Cichorium intybus L. has traditionally been used for its medicinal properties and contains various phytochemical and enzymatic compounds. The present study aimed to investigate the comparative effects of cantharidin and endothall with concentration of 2.5, 5.5 and 10 µg ml-1 on the changes in the gene expression of catalase and glutathione peroxidase. Furthermore, we assess the activities of these enzymes in the shoots and roots of Cichorium intybus L.. According to the findings, the expression of catalase and glutathione peroxidase increased in the samples treated with cantharidin more than endothall compared to the controls in both shoot (the most significant is in cantharidin with 2.5 µg ml-1 concentration) and root samples (the most significant is in cantharidin with 5.5 µg ml-1  concentration). In addition, the activity of catalase and concentrations of cantharidin (2.5 µg ml-1) in shoot samples led to the more intense stimulation of catalase and glutathione peroxidase compared to root samples. We suggest that cantharidin and endothall have negative effect on expression and absorption of antioxidant enzymes.https://journals.uni-lj.si/aas/article/view/12916cantharidincatalasecichorium intybus l.endothallglutathione reroxidase
spellingShingle Yalda GHOTBZADEH KERMANI
Ramazan Ali KHAVARI NEJAD
Homa MAHMOODZADEH
Khadijeh SHAHROKH ABADI
Comparative effects of cantharidin and endothall on gene expression and activity of antioxidant enzymes in Cichorium intybus L.
Acta Agriculturae Slovenica
cantharidin
catalase
cichorium intybus l.
endothall
glutathione reroxidase
title Comparative effects of cantharidin and endothall on gene expression and activity of antioxidant enzymes in Cichorium intybus L.
title_full Comparative effects of cantharidin and endothall on gene expression and activity of antioxidant enzymes in Cichorium intybus L.
title_fullStr Comparative effects of cantharidin and endothall on gene expression and activity of antioxidant enzymes in Cichorium intybus L.
title_full_unstemmed Comparative effects of cantharidin and endothall on gene expression and activity of antioxidant enzymes in Cichorium intybus L.
title_short Comparative effects of cantharidin and endothall on gene expression and activity of antioxidant enzymes in Cichorium intybus L.
title_sort comparative effects of cantharidin and endothall on gene expression and activity of antioxidant enzymes in cichorium intybus l
topic cantharidin
catalase
cichorium intybus l.
endothall
glutathione reroxidase
url https://journals.uni-lj.si/aas/article/view/12916
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