Synthesis of Silver Nanoparticles by Chemical Vapor Deposition Method and Its Application in Laser Desorption/Ionization Techniques

Laser desorption/ionization techniques, such as matrix-assisted laser desorption/ionization (MALDI) and surface-assisted laser desorption/ionization (SALDI), are the basis of modern mass spectrometry, enabling the analysis of a wide range of chemical compounds, from small molecules to biopolymers. M...

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Main Authors: Kinga Robotnik, Tomasz Zieliński, Justyna Walczak-Skierska, Ewelina Sibińska, Paulina Rudzik, Piotr Piszczek, Aleksandra Radtke, Paweł Piotr Pomastowski
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Nanomaterials
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Online Access:https://www.mdpi.com/2079-4991/15/13/973
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author Kinga Robotnik
Tomasz Zieliński
Justyna Walczak-Skierska
Ewelina Sibińska
Paulina Rudzik
Piotr Piszczek
Aleksandra Radtke
Paweł Piotr Pomastowski
author_facet Kinga Robotnik
Tomasz Zieliński
Justyna Walczak-Skierska
Ewelina Sibińska
Paulina Rudzik
Piotr Piszczek
Aleksandra Radtke
Paweł Piotr Pomastowski
author_sort Kinga Robotnik
collection DOAJ
description Laser desorption/ionization techniques, such as matrix-assisted laser desorption/ionization (MALDI) and surface-assisted laser desorption/ionization (SALDI), are the basis of modern mass spectrometry, enabling the analysis of a wide range of chemical compounds, from small molecules to biopolymers. MALDI uses organic matrices to support ionization, while SALDI relies on inorganic surfaces or nanomaterials, which reduce background and improve measurement sensitivity. This review focuses on the potential of using silver nanoparticles (AgNPs) in LDI-MS, with particular emphasis on their synthesis from the gas phase (CVD, Chemical Vapor Deposition). The key role of nanostructures in increasing ionization efficiency and analytical selectivity is emphasized. The CVD technique enables precise control over the morphology, size, and distribution of nanoparticles, which translates into better repeatability and sensitivity of nanostructure-assisted laser desorption/ionization mass spectrometry (NALDI-MS) measurements. The latest achievements in this field are presented, as well as potential applications of CVD-produced AgNPs in analytical chemistry, environmental analysis, and the petrochemical industry.
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institution OA Journals
issn 2079-4991
language English
publishDate 2025-06-01
publisher MDPI AG
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series Nanomaterials
spelling doaj-art-cdb32a2273ab47a8a903cf37fc2404602025-08-20T02:36:27ZengMDPI AGNanomaterials2079-49912025-06-01151397310.3390/nano15130973Synthesis of Silver Nanoparticles by Chemical Vapor Deposition Method and Its Application in Laser Desorption/Ionization TechniquesKinga Robotnik0Tomasz Zieliński1Justyna Walczak-Skierska2Ewelina Sibińska3Paulina Rudzik4Piotr Piszczek5Aleksandra Radtke6Paweł Piotr Pomastowski7Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, Wileńska 4 Str., 87-100 Toruń, PolandEnergy Efficiency Project Coordination Team, ORLEN S.A., Chemików 7 Str., 09-411 Płock, PolandCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, Wileńska 4 Str., 87-100 Toruń, PolandCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, Wileńska 4 Str., 87-100 Toruń, PolandDepartment of Inorganic and Coordination Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7 Str., 87-100 Toruń, PolandDepartment of Inorganic and Coordination Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7 Str., 87-100 Toruń, PolandDepartment of Inorganic and Coordination Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7 Str., 87-100 Toruń, PolandCentre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, Wileńska 4 Str., 87-100 Toruń, PolandLaser desorption/ionization techniques, such as matrix-assisted laser desorption/ionization (MALDI) and surface-assisted laser desorption/ionization (SALDI), are the basis of modern mass spectrometry, enabling the analysis of a wide range of chemical compounds, from small molecules to biopolymers. MALDI uses organic matrices to support ionization, while SALDI relies on inorganic surfaces or nanomaterials, which reduce background and improve measurement sensitivity. This review focuses on the potential of using silver nanoparticles (AgNPs) in LDI-MS, with particular emphasis on their synthesis from the gas phase (CVD, Chemical Vapor Deposition). The key role of nanostructures in increasing ionization efficiency and analytical selectivity is emphasized. The CVD technique enables precise control over the morphology, size, and distribution of nanoparticles, which translates into better repeatability and sensitivity of nanostructure-assisted laser desorption/ionization mass spectrometry (NALDI-MS) measurements. The latest achievements in this field are presented, as well as potential applications of CVD-produced AgNPs in analytical chemistry, environmental analysis, and the petrochemical industry.https://www.mdpi.com/2079-4991/15/13/973silver nanoparticlesCVDLDI-MSNALDIMALDI
spellingShingle Kinga Robotnik
Tomasz Zieliński
Justyna Walczak-Skierska
Ewelina Sibińska
Paulina Rudzik
Piotr Piszczek
Aleksandra Radtke
Paweł Piotr Pomastowski
Synthesis of Silver Nanoparticles by Chemical Vapor Deposition Method and Its Application in Laser Desorption/Ionization Techniques
Nanomaterials
silver nanoparticles
CVD
LDI-MS
NALDI
MALDI
title Synthesis of Silver Nanoparticles by Chemical Vapor Deposition Method and Its Application in Laser Desorption/Ionization Techniques
title_full Synthesis of Silver Nanoparticles by Chemical Vapor Deposition Method and Its Application in Laser Desorption/Ionization Techniques
title_fullStr Synthesis of Silver Nanoparticles by Chemical Vapor Deposition Method and Its Application in Laser Desorption/Ionization Techniques
title_full_unstemmed Synthesis of Silver Nanoparticles by Chemical Vapor Deposition Method and Its Application in Laser Desorption/Ionization Techniques
title_short Synthesis of Silver Nanoparticles by Chemical Vapor Deposition Method and Its Application in Laser Desorption/Ionization Techniques
title_sort synthesis of silver nanoparticles by chemical vapor deposition method and its application in laser desorption ionization techniques
topic silver nanoparticles
CVD
LDI-MS
NALDI
MALDI
url https://www.mdpi.com/2079-4991/15/13/973
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