Synthesis of Some 2-Thioxo-imidazolidin-4-one Derivatives and its Antimicrobial Activity
Series of newly prepared 3-{[2,6-bis(4-substituted phenyl)-1- methylpiperidin-4- ylidene] amino}- 2-thioxo-imidazolidin-4-one derivatives (3a-3f) have been synthesized by the cyclization of compound (2a-2f), ethyl chloro acetate and fused sodium acetate. The chemical structures were confirmed by IR,...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2010/292461 |
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| author | A. Jamal Abdul Nasser A. Idhayadhulla R. Surendra Kumar J. Selvin |
| author_facet | A. Jamal Abdul Nasser A. Idhayadhulla R. Surendra Kumar J. Selvin |
| author_sort | A. Jamal Abdul Nasser |
| collection | DOAJ |
| description | Series of newly prepared 3-{[2,6-bis(4-substituted phenyl)-1- methylpiperidin-4- ylidene] amino}- 2-thioxo-imidazolidin-4-one derivatives (3a-3f) have been synthesized by the cyclization of compound (2a-2f), ethyl chloro acetate and fused sodium acetate. The chemical structures were confirmed by IR, 1H NMR and elemental analysis. The synthesized compounds were screened for their antimicrobial activity against four antibacterial and four antifungal organisms. |
| format | Article |
| id | doaj-art-cdb31eded8cc4296bbafbee1e1926ba2 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-cdb31eded8cc4296bbafbee1e1926ba22025-02-03T06:01:40ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-01741320132510.1155/2010/292461Synthesis of Some 2-Thioxo-imidazolidin-4-one Derivatives and its Antimicrobial ActivityA. Jamal Abdul Nasser0A. Idhayadhulla1R. Surendra Kumar2J. Selvin3P.G & Research Department of Chemistry, Jamal Mohamed College, Tiruchirapalli-620020, Tamilnadu, IndiaP.G & Research Department of Chemistry, Jamal Mohamed College, Tiruchirapalli-620020, Tamilnadu, IndiaP.G & Research Department of Chemistry, Jamal Mohamed College, Tiruchirapalli-620020, Tamilnadu, IndiaDepartment of Microbiology, Bharathidasan University, Tiruchirapalli-620024, Tamilnadu, IndiaSeries of newly prepared 3-{[2,6-bis(4-substituted phenyl)-1- methylpiperidin-4- ylidene] amino}- 2-thioxo-imidazolidin-4-one derivatives (3a-3f) have been synthesized by the cyclization of compound (2a-2f), ethyl chloro acetate and fused sodium acetate. The chemical structures were confirmed by IR, 1H NMR and elemental analysis. The synthesized compounds were screened for their antimicrobial activity against four antibacterial and four antifungal organisms.http://dx.doi.org/10.1155/2010/292461 |
| spellingShingle | A. Jamal Abdul Nasser A. Idhayadhulla R. Surendra Kumar J. Selvin Synthesis of Some 2-Thioxo-imidazolidin-4-one Derivatives and its Antimicrobial Activity E-Journal of Chemistry |
| title | Synthesis of Some 2-Thioxo-imidazolidin-4-one Derivatives and its Antimicrobial Activity |
| title_full | Synthesis of Some 2-Thioxo-imidazolidin-4-one Derivatives and its Antimicrobial Activity |
| title_fullStr | Synthesis of Some 2-Thioxo-imidazolidin-4-one Derivatives and its Antimicrobial Activity |
| title_full_unstemmed | Synthesis of Some 2-Thioxo-imidazolidin-4-one Derivatives and its Antimicrobial Activity |
| title_short | Synthesis of Some 2-Thioxo-imidazolidin-4-one Derivatives and its Antimicrobial Activity |
| title_sort | synthesis of some 2 thioxo imidazolidin 4 one derivatives and its antimicrobial activity |
| url | http://dx.doi.org/10.1155/2010/292461 |
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