Predictors of Immune Fitness and the Alcohol Hangover: Survey Data from UK and Irish Adults

Immune fitness is defined as the capacity of the body to respond to health challenges (such as infections) by activating an appropriate immune response to promote health and prevent and resolve disease, which is essential for improving quality of life. Thus, immune fitness plays an essential role in...

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Main Authors: Joris C. Verster, Agnese Merlo, Maureen N. Zijlstra, Benthe R. C. van der Weij, Anne S. Boogaard, Sanne E. Schulz, Jessica Balikji, Andy J. Kim, Sherry H. Stewart, Simon B. Sherry, Johan Garssen, Gillian Bruce, Lydia E. Devenney
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Data
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Online Access:https://www.mdpi.com/2306-5729/10/4/49
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author Joris C. Verster
Agnese Merlo
Maureen N. Zijlstra
Benthe R. C. van der Weij
Anne S. Boogaard
Sanne E. Schulz
Jessica Balikji
Andy J. Kim
Sherry H. Stewart
Simon B. Sherry
Johan Garssen
Gillian Bruce
Lydia E. Devenney
author_facet Joris C. Verster
Agnese Merlo
Maureen N. Zijlstra
Benthe R. C. van der Weij
Anne S. Boogaard
Sanne E. Schulz
Jessica Balikji
Andy J. Kim
Sherry H. Stewart
Simon B. Sherry
Johan Garssen
Gillian Bruce
Lydia E. Devenney
author_sort Joris C. Verster
collection DOAJ
description Immune fitness is defined as the capacity of the body to respond to health challenges (such as infections) by activating an appropriate immune response to promote health and prevent and resolve disease, which is essential for improving quality of life. Thus, immune fitness plays an essential role in health, and reduced immune fitness may be an important signal of increased susceptibility for disease. Lifestyle factors such as increased levels of alcohol consumption have been shown to negatively impact immune fitness. The alcohol hangover is the most frequently reported negative consequence of alcohol consumption and is defined as the combination of negative mental and physical symptoms, which can be experienced after a single episode of alcohol consumption, starting when blood alcohol concentration (BAC) approaches zero. Significant correlations have been reported between hangover severity and both immune fitness and biomarkers of systemic inflammation. The concepts of immune fitness and alcohol hangover are further linked by the fact that the inflammatory response to alcohol consumption plays an important role in the pathology of the alcohol hangover. Moreover, immune fitness has been related to the susceptibility of experiencing hangovers per se. It is therefore important to investigate the interrelationship between immune fitness and the alcohol hangover, and to identify possible predictor variables of both constructs. This data descriptor article describes a study that was conducted with adults living in the UK or Ireland, evaluating possible correlates and predictors of immune fitness and the alcohol hangover. Data on mood, personality, mental resilience, pain catastrophizing, and sleep were collected from <i>n</i> = 1178 participants through an online survey. Herein, the survey and corresponding dataset are described.
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spelling doaj-art-cdb190bd5a5e40a5ad30f7000dc80d142025-08-20T03:13:49ZengMDPI AGData2306-57292025-04-011044910.3390/data10040049Predictors of Immune Fitness and the Alcohol Hangover: Survey Data from UK and Irish AdultsJoris C. Verster0Agnese Merlo1Maureen N. Zijlstra2Benthe R. C. van der Weij3Anne S. Boogaard4Sanne E. Schulz5Jessica Balikji6Andy J. Kim7Sherry H. Stewart8Simon B. Sherry9Johan Garssen10Gillian Bruce11Lydia E. Devenney12Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584 CG Utrecht, The NetherlandsDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584 CG Utrecht, The NetherlandsDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584 CG Utrecht, The NetherlandsDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584 CG Utrecht, The NetherlandsDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584 CG Utrecht, The NetherlandsDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584 CG Utrecht, The NetherlandsDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584 CG Utrecht, The NetherlandsDepartment of Psychology and Neuroscience, Dalhousie University, 1355 Oxford St, Halifax, NS B3H 4R2, CanadaDepartment of Psychology and Neuroscience, Dalhousie University, 1355 Oxford St, Halifax, NS B3H 4R2, CanadaDepartment of Psychology and Neuroscience, Dalhousie University, 1355 Oxford St, Halifax, NS B3H 4R2, CanadaDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, 3584 CG Utrecht, The NetherlandsSchool of Education and Social Sciences, University of the West of Scotland, Paisley PA1 2BE, UKDepartment of Psychology and Counselling, Faculty of Arts and Social Sciences, The Open University, Milton Keynes MK7 6AA, UKImmune fitness is defined as the capacity of the body to respond to health challenges (such as infections) by activating an appropriate immune response to promote health and prevent and resolve disease, which is essential for improving quality of life. Thus, immune fitness plays an essential role in health, and reduced immune fitness may be an important signal of increased susceptibility for disease. Lifestyle factors such as increased levels of alcohol consumption have been shown to negatively impact immune fitness. The alcohol hangover is the most frequently reported negative consequence of alcohol consumption and is defined as the combination of negative mental and physical symptoms, which can be experienced after a single episode of alcohol consumption, starting when blood alcohol concentration (BAC) approaches zero. Significant correlations have been reported between hangover severity and both immune fitness and biomarkers of systemic inflammation. The concepts of immune fitness and alcohol hangover are further linked by the fact that the inflammatory response to alcohol consumption plays an important role in the pathology of the alcohol hangover. Moreover, immune fitness has been related to the susceptibility of experiencing hangovers per se. It is therefore important to investigate the interrelationship between immune fitness and the alcohol hangover, and to identify possible predictor variables of both constructs. This data descriptor article describes a study that was conducted with adults living in the UK or Ireland, evaluating possible correlates and predictors of immune fitness and the alcohol hangover. Data on mood, personality, mental resilience, pain catastrophizing, and sleep were collected from <i>n</i> = 1178 participants through an online survey. Herein, the survey and corresponding dataset are described.https://www.mdpi.com/2306-5729/10/4/49immune fitnessalcoholhangovermoodanxietypersonality
spellingShingle Joris C. Verster
Agnese Merlo
Maureen N. Zijlstra
Benthe R. C. van der Weij
Anne S. Boogaard
Sanne E. Schulz
Jessica Balikji
Andy J. Kim
Sherry H. Stewart
Simon B. Sherry
Johan Garssen
Gillian Bruce
Lydia E. Devenney
Predictors of Immune Fitness and the Alcohol Hangover: Survey Data from UK and Irish Adults
Data
immune fitness
alcohol
hangover
mood
anxiety
personality
title Predictors of Immune Fitness and the Alcohol Hangover: Survey Data from UK and Irish Adults
title_full Predictors of Immune Fitness and the Alcohol Hangover: Survey Data from UK and Irish Adults
title_fullStr Predictors of Immune Fitness and the Alcohol Hangover: Survey Data from UK and Irish Adults
title_full_unstemmed Predictors of Immune Fitness and the Alcohol Hangover: Survey Data from UK and Irish Adults
title_short Predictors of Immune Fitness and the Alcohol Hangover: Survey Data from UK and Irish Adults
title_sort predictors of immune fitness and the alcohol hangover survey data from uk and irish adults
topic immune fitness
alcohol
hangover
mood
anxiety
personality
url https://www.mdpi.com/2306-5729/10/4/49
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