Immune response and safety of co-administered Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis vaccines in goats
Background: Infectious diseases such as Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis have considerable impacts on the optimal utilization of sheep and goat resources in Ethiopia. Immunization using multiple vaccines administered simultaneous...
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| Format: | Article |
| Language: | English |
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Tripoli University
2024-08-01
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| Series: | Open Veterinary Journal |
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| Online Access: | https://www.openveterinaryjournal.com/?mno=201682 |
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| author | Takele Tesgera Hurisa Takele Abayneh Tefera Retta Negatu Teshale Sori Berecha Bayisa Deme Mirtneh Akalu Yilma Wondwossen Tolossa Abinet Legesse Ashetu Negewo Wubet W/Medhin Kedir Sherefa Getu Ayele Adugna Geresu Eyob Assefa Dawit Dufera |
| author_facet | Takele Tesgera Hurisa Takele Abayneh Tefera Retta Negatu Teshale Sori Berecha Bayisa Deme Mirtneh Akalu Yilma Wondwossen Tolossa Abinet Legesse Ashetu Negewo Wubet W/Medhin Kedir Sherefa Getu Ayele Adugna Geresu Eyob Assefa Dawit Dufera |
| author_sort | Takele Tesgera Hurisa |
| collection | DOAJ |
| description | Background:
Infectious diseases such as Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis have considerable impacts on the optimal utilization of sheep and goat resources in Ethiopia. Immunization using multiple vaccines administered simultaneously has been suggested as a cost-effective and safe approach to controlling and preventing these diseases.
Aim:
The aim of this study was to assess the immunogenicity and safety of multiple vaccines administered simultaneously in goats.
Methods:
Sero-negative Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis goats were immunized with multiple vaccines. Goats vaccinated with a single vaccine against each disease served as a positive control. The immune response of the goats was assessed using serological tests, and any adverse effects were monitored.
Results:
The results of the present study showed that goats vaccinated with multiple vaccines exhibited a remarkable immune response against Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, and Pasteurellosis. In contrast, they did not produce protective immune response against sheep or goat pox. No adverse effects were observed with any of the vaccines.
Conclusion:
This study suggested that combined vaccines can be effective at inducing a protective immune response in goats. However, further research is needed to fully understand the immune response to combined vaccines. [Open Vet J 2024; 14(8.000): 1960-1967] |
| format | Article |
| id | doaj-art-cdac4d765af84d9ba2dc76acb4020853 |
| institution | OA Journals |
| issn | 2226-4485 2218-6050 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | Tripoli University |
| record_format | Article |
| series | Open Veterinary Journal |
| spelling | doaj-art-cdac4d765af84d9ba2dc76acb40208532025-08-20T01:47:36ZengTripoli UniversityOpen Veterinary Journal2226-44852218-60502024-08-011481960196710.5455/OVJ.2024.v14.i8.25201682Immune response and safety of co-administered Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis vaccines in goatsTakele Tesgera Hurisa0Takele Abayneh Tefera1Retta Negatu2Teshale Sori3Berecha Bayisa Deme4Mirtneh Akalu Yilma5Wondwossen Tolossa6Abinet Legesse7Ashetu Negewo8Wubet W/Medhin9Kedir Sherefa10Getu Ayele11Adugna Geresu12Eyob Assefa13Dawit DuferaNational Veterinary Institute National Veterinary Institute Luna export Abattoir Addis Ababa University College of Veterinary Medicine, Department of Clinical Studies National Veterinary Institute National Veterinary Institute National Veterinary Institute National Veterinary Institute National Veterinary Institute National Veterinary Institute National Veterinary Institute National Veterinary Institute National Veterinary Institute National Veterinary InstituteBackground: Infectious diseases such as Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis have considerable impacts on the optimal utilization of sheep and goat resources in Ethiopia. Immunization using multiple vaccines administered simultaneously has been suggested as a cost-effective and safe approach to controlling and preventing these diseases. Aim: The aim of this study was to assess the immunogenicity and safety of multiple vaccines administered simultaneously in goats. Methods: Sero-negative Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis goats were immunized with multiple vaccines. Goats vaccinated with a single vaccine against each disease served as a positive control. The immune response of the goats was assessed using serological tests, and any adverse effects were monitored. Results: The results of the present study showed that goats vaccinated with multiple vaccines exhibited a remarkable immune response against Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, and Pasteurellosis. In contrast, they did not produce protective immune response against sheep or goat pox. No adverse effects were observed with any of the vaccines. Conclusion: This study suggested that combined vaccines can be effective at inducing a protective immune response in goats. However, further research is needed to fully understand the immune response to combined vaccines. [Open Vet J 2024; 14(8.000): 1960-1967]https://www.openveterinaryjournal.com/?mno=201682immunogenicitysafetygoatsmultiple vaccinesethiopia |
| spellingShingle | Takele Tesgera Hurisa Takele Abayneh Tefera Retta Negatu Teshale Sori Berecha Bayisa Deme Mirtneh Akalu Yilma Wondwossen Tolossa Abinet Legesse Ashetu Negewo Wubet W/Medhin Kedir Sherefa Getu Ayele Adugna Geresu Eyob Assefa Dawit Dufera Immune response and safety of co-administered Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis vaccines in goats Open Veterinary Journal immunogenicity safety goats multiple vaccines ethiopia |
| title | Immune response and safety of co-administered Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis vaccines in goats |
| title_full | Immune response and safety of co-administered Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis vaccines in goats |
| title_fullStr | Immune response and safety of co-administered Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis vaccines in goats |
| title_full_unstemmed | Immune response and safety of co-administered Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis vaccines in goats |
| title_short | Immune response and safety of co-administered Peste des Petits Ruminants, Contagious Caprine Pleuropneumonia, Sheep and Goat Pox, and Pasteurellosis vaccines in goats |
| title_sort | immune response and safety of co administered peste des petits ruminants contagious caprine pleuropneumonia sheep and goat pox and pasteurellosis vaccines in goats |
| topic | immunogenicity safety goats multiple vaccines ethiopia |
| url | https://www.openveterinaryjournal.com/?mno=201682 |
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