Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis
A 53-year-old woman is admitted with a serum creatinine of 16 mg/dl. Seven months earlier, she was diagnosed with heart failure and started on several medications, including Hydralazine. Laboratory studies revealed the presence of dual Anti-Neutrophil Cytoplasmic Antibodies (anti-MPO and anti-PR3),...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2019/8720837 |
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| _version_ | 1832561246755356672 |
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| author | D. Lai N. Dave R. Raghavan |
| author_facet | D. Lai N. Dave R. Raghavan |
| author_sort | D. Lai |
| collection | DOAJ |
| description | A 53-year-old woman is admitted with a serum creatinine of 16 mg/dl. Seven months earlier, she was diagnosed with heart failure and started on several medications, including Hydralazine. Laboratory studies revealed the presence of dual Anti-Neutrophil Cytoplasmic Antibodies (anti-MPO and anti-PR3), anti-nuclear and anti-histone antibodies. The clinical diagnosis was Drug-Induced ANCA Vasculitis (DIAV). Kidney histology, however, did not reveal crescents, but showed characteristic features of Alport’s syndrome. |
| format | Article |
| id | doaj-art-cd8dc77a6dd045d18db790ab1a0abca3 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-cd8dc77a6dd045d18db790ab1a0abca32025-02-03T01:25:35ZengWileyCase Reports in Nephrology2090-66412090-665X2019-01-01201910.1155/2019/87208378720837Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced VasculitisD. Lai0N. Dave1R. Raghavan2Baylor College of Medicine, Houston, TX 77030, USABaylor College of Medicine, Houston, TX 77030, USABaylor College of Medicine, Houston, TX 77030, USAA 53-year-old woman is admitted with a serum creatinine of 16 mg/dl. Seven months earlier, she was diagnosed with heart failure and started on several medications, including Hydralazine. Laboratory studies revealed the presence of dual Anti-Neutrophil Cytoplasmic Antibodies (anti-MPO and anti-PR3), anti-nuclear and anti-histone antibodies. The clinical diagnosis was Drug-Induced ANCA Vasculitis (DIAV). Kidney histology, however, did not reveal crescents, but showed characteristic features of Alport’s syndrome.http://dx.doi.org/10.1155/2019/8720837 |
| spellingShingle | D. Lai N. Dave R. Raghavan Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis Case Reports in Nephrology |
| title | Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis |
| title_full | Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis |
| title_fullStr | Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis |
| title_full_unstemmed | Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis |
| title_short | Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis |
| title_sort | incidentally diagnosed alport syndrome in a patient with drug induced vasculitis |
| url | http://dx.doi.org/10.1155/2019/8720837 |
| work_keys_str_mv | AT dlai incidentallydiagnosedalportsyndromeinapatientwithdruginducedvasculitis AT ndave incidentallydiagnosedalportsyndromeinapatientwithdruginducedvasculitis AT rraghavan incidentallydiagnosedalportsyndromeinapatientwithdruginducedvasculitis |