APPLICATION OF POLYESTER-BASED MEMBRANES IN PERIODONTAL REGENERATIVE THERAPY: A SYSTEMATIC REVIEW OF CLINICAL STUDIES
Background: To successfully regenerate lost tissues in periodontal therapy, the bone defect must be isolated from the surrounding tissues. For this purpose, various types of barrier membranes have been developed and are being applied. Biodegradable membranes of synthetic origin are of particular int...
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| Language: | English |
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Romanian Society of Oral Rehabilitation
2025-06-01
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| Series: | Romanian Journal of Oral Rehabilitation |
| Online Access: | https://rjor.ro/application-of-polyester-based-membranes-in-periodontal-regenerative-therapy-a-systematic-review-of-clinical-studies/ |
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| author | Elitsa Sabeva Dimitar Dochev |
| author_facet | Elitsa Sabeva Dimitar Dochev |
| author_sort | Elitsa Sabeva |
| collection | DOAJ |
| description | Background: To successfully regenerate lost tissues in periodontal therapy, the bone defect must be isolated from the surrounding tissues. For this purpose, various types of barrier membranes have been developed and are being applied. Biodegradable membranes of synthetic origin are of particular interest since their properties can be controlled by modifying their composition and structure. Important representatives of this group are the polyester membranes. Aim of the study: This systematic review aims to investigate the types and effectiveness of polyester membranes used in periodontal regenerative therapy over the last ten years according to the published clinical studies. Materials and methods: The advanced search was conducted on 07 February 2025 using the PubMed, Web of Science, and Scopus databases and adhering to PRISMA guidelines. Results: This study included 256 cases, in 42.8% of which a biodegradable barrier membrane made copolymer of polylactic acid with polyglycolic acid (PLA-PGA) was applied. In over 36% of the cases, a polylactic acid (PLA) was used. In 41.8% of the cases, a polyester membrane was applied without bone graft. Conclusions: Polyester membranes are successfully used in periodontal regenerative therapy. They are characterized by high biocompatibility, good barrier function, controlled biodegradability, and suitable mechanical properties. In the last twenty years, PLA or its copolymers have been commonly used in clinical studies, and this type of biodegradable membrane is usually combined with various bone grafts. |
| format | Article |
| id | doaj-art-cd82392ab7c24de9a9ab7acfc25f482a |
| institution | Kabale University |
| issn | 2066-7000 2601-4661 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Romanian Society of Oral Rehabilitation |
| record_format | Article |
| series | Romanian Journal of Oral Rehabilitation |
| spelling | doaj-art-cd82392ab7c24de9a9ab7acfc25f482a2025-08-20T03:36:35ZengRomanian Society of Oral RehabilitationRomanian Journal of Oral Rehabilitation2066-70002601-46612025-06-01172304010.62610/RJOR.2025.2.17.2APPLICATION OF POLYESTER-BASED MEMBRANES IN PERIODONTAL REGENERATIVE THERAPY: A SYSTEMATIC REVIEW OF CLINICAL STUDIESElitsa Sabeva0Dimitar Dochev1"Department of Periodontology and Dental Implantology, Faculty of Dental Medicine, Medical University of Varna, Varna, Bulgaria""Department of Orthopedics and Traumatology, Naval Hospital Varna, Military Medical Academy Sofia, Bulgaria"Background: To successfully regenerate lost tissues in periodontal therapy, the bone defect must be isolated from the surrounding tissues. For this purpose, various types of barrier membranes have been developed and are being applied. Biodegradable membranes of synthetic origin are of particular interest since their properties can be controlled by modifying their composition and structure. Important representatives of this group are the polyester membranes. Aim of the study: This systematic review aims to investigate the types and effectiveness of polyester membranes used in periodontal regenerative therapy over the last ten years according to the published clinical studies. Materials and methods: The advanced search was conducted on 07 February 2025 using the PubMed, Web of Science, and Scopus databases and adhering to PRISMA guidelines. Results: This study included 256 cases, in 42.8% of which a biodegradable barrier membrane made copolymer of polylactic acid with polyglycolic acid (PLA-PGA) was applied. In over 36% of the cases, a polylactic acid (PLA) was used. In 41.8% of the cases, a polyester membrane was applied without bone graft. Conclusions: Polyester membranes are successfully used in periodontal regenerative therapy. They are characterized by high biocompatibility, good barrier function, controlled biodegradability, and suitable mechanical properties. In the last twenty years, PLA or its copolymers have been commonly used in clinical studies, and this type of biodegradable membrane is usually combined with various bone grafts.https://rjor.ro/application-of-polyester-based-membranes-in-periodontal-regenerative-therapy-a-systematic-review-of-clinical-studies/ |
| spellingShingle | Elitsa Sabeva Dimitar Dochev APPLICATION OF POLYESTER-BASED MEMBRANES IN PERIODONTAL REGENERATIVE THERAPY: A SYSTEMATIC REVIEW OF CLINICAL STUDIES Romanian Journal of Oral Rehabilitation |
| title | APPLICATION OF POLYESTER-BASED MEMBRANES IN PERIODONTAL REGENERATIVE THERAPY: A SYSTEMATIC REVIEW OF CLINICAL STUDIES |
| title_full | APPLICATION OF POLYESTER-BASED MEMBRANES IN PERIODONTAL REGENERATIVE THERAPY: A SYSTEMATIC REVIEW OF CLINICAL STUDIES |
| title_fullStr | APPLICATION OF POLYESTER-BASED MEMBRANES IN PERIODONTAL REGENERATIVE THERAPY: A SYSTEMATIC REVIEW OF CLINICAL STUDIES |
| title_full_unstemmed | APPLICATION OF POLYESTER-BASED MEMBRANES IN PERIODONTAL REGENERATIVE THERAPY: A SYSTEMATIC REVIEW OF CLINICAL STUDIES |
| title_short | APPLICATION OF POLYESTER-BASED MEMBRANES IN PERIODONTAL REGENERATIVE THERAPY: A SYSTEMATIC REVIEW OF CLINICAL STUDIES |
| title_sort | application of polyester based membranes in periodontal regenerative therapy a systematic review of clinical studies |
| url | https://rjor.ro/application-of-polyester-based-membranes-in-periodontal-regenerative-therapy-a-systematic-review-of-clinical-studies/ |
| work_keys_str_mv | AT elitsasabeva applicationofpolyesterbasedmembranesinperiodontalregenerativetherapyasystematicreviewofclinicalstudies AT dimitardochev applicationofpolyesterbasedmembranesinperiodontalregenerativetherapyasystematicreviewofclinicalstudies |