Causes and Treatment of Acute Renal Failure in Children

Objective: to study the causes of acute renal failure (ARF) in children and to substantiate recommendations on its treatment. Fifty-nine children with ARF were followed up in 1979 to 2004. In 90% of the patients, ARF was established to be caused by hemolytic uremic syndrome (HUS), acute intestinal i...

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Main Authors: O. I. Andriyanova, F. K. Manerov, Yu. A. Churlyaev, I. G. Khamin
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2007-08-01
Series:Общая реаниматология
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Online Access:https://www.reanimatology.com/rmt/article/view/971
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author O. I. Andriyanova
F. K. Manerov
Yu. A. Churlyaev
I. G. Khamin
author_facet O. I. Andriyanova
F. K. Manerov
Yu. A. Churlyaev
I. G. Khamin
author_sort O. I. Andriyanova
collection DOAJ
description Objective: to study the causes of acute renal failure (ARF) in children and to substantiate recommendations on its treatment. Fifty-nine children with ARF were followed up in 1979 to 2004. In 90% of the patients, ARF was established to be caused by hemolytic uremic syndrome (HUS), acute intestinal infection (AII), acute glomerulonephritis, and acute intravascular hemolysis. The major cause of ARF was AII in two thirds (66.1%) of the children. In the past decade, the incidence of HUS has decreased from 55 to 40%. The authors identified the following predictors of poor ARF outcome: early age, anuria, impaired consciousness progressing to spoor and coma. A combination of these symptoms is most frequently observed in patients with HUS in which the kidneys are the major target organ and the possibilities of more than 7-day treatment for anuria without dialysis are limited. In other etiology of ARF, water deprivation, antihypertensive therapy, and exchange plasmapheresis allow patients to survive until renal function restores without renal replacement therapy, by preventing serious complications.
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publishDate 2007-08-01
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spelling doaj-art-cd7cf23ff8bd4b359c58fe2a4264f1532025-08-20T03:59:40ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102007-08-0134707510.15360/1813-9779-2007-4-70-75971Causes and Treatment of Acute Renal Failure in ChildrenO. I. Andriyanova0F. K. Manerov1Yu. A. Churlyaev2I. G. Khamin3Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, Department of Postgraduate Training of Physicians, NovokuznetskBranch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, Department of Postgraduate Training of Physicians, NovokuznetskBranch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, Department of Postgraduate Training of Physicians, NovokuznetskBranch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, Department of Postgraduate Training of Physicians, NovokuznetskObjective: to study the causes of acute renal failure (ARF) in children and to substantiate recommendations on its treatment. Fifty-nine children with ARF were followed up in 1979 to 2004. In 90% of the patients, ARF was established to be caused by hemolytic uremic syndrome (HUS), acute intestinal infection (AII), acute glomerulonephritis, and acute intravascular hemolysis. The major cause of ARF was AII in two thirds (66.1%) of the children. In the past decade, the incidence of HUS has decreased from 55 to 40%. The authors identified the following predictors of poor ARF outcome: early age, anuria, impaired consciousness progressing to spoor and coma. A combination of these symptoms is most frequently observed in patients with HUS in which the kidneys are the major target organ and the possibilities of more than 7-day treatment for anuria without dialysis are limited. In other etiology of ARF, water deprivation, antihypertensive therapy, and exchange plasmapheresis allow patients to survive until renal function restores without renal replacement therapy, by preventing serious complications.https://www.reanimatology.com/rmt/article/view/971cortical necrosisacute renal failurehemolytic uremic syndromerenal replacement therapyplasmapheresis
spellingShingle O. I. Andriyanova
F. K. Manerov
Yu. A. Churlyaev
I. G. Khamin
Causes and Treatment of Acute Renal Failure in Children
Общая реаниматология
cortical necrosis
acute renal failure
hemolytic uremic syndrome
renal replacement therapy
plasmapheresis
title Causes and Treatment of Acute Renal Failure in Children
title_full Causes and Treatment of Acute Renal Failure in Children
title_fullStr Causes and Treatment of Acute Renal Failure in Children
title_full_unstemmed Causes and Treatment of Acute Renal Failure in Children
title_short Causes and Treatment of Acute Renal Failure in Children
title_sort causes and treatment of acute renal failure in children
topic cortical necrosis
acute renal failure
hemolytic uremic syndrome
renal replacement therapy
plasmapheresis
url https://www.reanimatology.com/rmt/article/view/971
work_keys_str_mv AT oiandriyanova causesandtreatmentofacuterenalfailureinchildren
AT fkmanerov causesandtreatmentofacuterenalfailureinchildren
AT yuachurlyaev causesandtreatmentofacuterenalfailureinchildren
AT igkhamin causesandtreatmentofacuterenalfailureinchildren