Conjugation of Triterpenic Acids with 3-Aminoquinuclidine Moiety: An Approach to Acetylcholinesterase Mixed or Uncompetitive Type Inhibitors

Conjugation of Triterpenic Acids with 3-Aminoquinuclidine Moiety: An Approach to Acetylcholinesterase Mixed or Uncompetitive Type Inhibitors

Alzheimer’s disease (AD) poses a significant public health issue. Despite the fact that today there are several methods of maintenance therapy, one of the most widely used methods is designed to correct the deficiency of acetylcholine. In the search for new potential inhibitors of cholinesterase enz...

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Bibliographic Details
Main Authors: Anastasiya V. Petrova, Ha T. T. Nguyen, Irina V. Zueva, Konstantin A. Petrov, Alexander N. Lobov, Oxana B. Kazakova
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
triterpenoids
lupane
oleanane
ursane
3-aminoquinuclidine
acetylcholinesterase
Online Access:https://www.mdpi.com/1420-3049/30/1/95
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