Preparation, Characterisation and Antimicrobial Activities of Some Novel Nitriles and Imidazolines
Reaction between 5-methyl-3-aminoisoxazole and ?-acetamidophenylsulpho-nylchloride yielded compound 1. Hydrolysis of compound 1 gave a starting compound 4-methoxybenzal-?-5-methyl isoxazol-3-yl-sulphonamido aniline 2. The compound 2 on condensation with different aldehydes and potassium cyanide yiel...
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| Format: | Article |
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| Language: | English |
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University of Tehran
2004-06-01
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| Series: | Journal of Sciences, Islamic Republic of Iran |
| Online Access: | https://jsciences.ut.ac.ir/article_31592_12625934005ff16320982e9f0d050eb9.pdf |
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| description | Reaction between 5-methyl-3-aminoisoxazole and ?-acetamidophenylsulpho-nylchloride yielded compound 1. Hydrolysis of compound 1 gave a starting compound 4-methoxybenzal-?-5-methyl isoxazol-3-yl-sulphonamido aniline 2. The compound 2 on condensation with different aldehydes and potassium cyanide yielded the nitriles 3a-l. Cyclocondensation between oxazolinone and compound 2 yielded imidazolines 4a-l. All compounds have been characterised using IR, 1H NMR and Mass spectral data and have been evaluated for their antimicrobial activity against different strains of bacteria and fungi. |
| format | Article |
| id | doaj-art-cd69c1351fe449bba5bebd405976aee1 |
| institution | OA Journals |
| issn | 1016-1104 2345-6914 |
| language | English |
| publishDate | 2004-06-01 |
| publisher | University of Tehran |
| record_format | Article |
| series | Journal of Sciences, Islamic Republic of Iran |
| spelling | doaj-art-cd69c1351fe449bba5bebd405976aee12025-08-20T02:25:51ZengUniversity of TehranJournal of Sciences, Islamic Republic of Iran1016-11042345-69142004-06-0115231592Preparation, Characterisation and Antimicrobial Activities of Some Novel Nitriles and ImidazolinesReaction between 5-methyl-3-aminoisoxazole and ?-acetamidophenylsulpho-nylchloride yielded compound 1. Hydrolysis of compound 1 gave a starting compound 4-methoxybenzal-?-5-methyl isoxazol-3-yl-sulphonamido aniline 2. The compound 2 on condensation with different aldehydes and potassium cyanide yielded the nitriles 3a-l. Cyclocondensation between oxazolinone and compound 2 yielded imidazolines 4a-l. All compounds have been characterised using IR, 1H NMR and Mass spectral data and have been evaluated for their antimicrobial activity against different strains of bacteria and fungi.https://jsciences.ut.ac.ir/article_31592_12625934005ff16320982e9f0d050eb9.pdf |
| spellingShingle | Preparation, Characterisation and Antimicrobial Activities of Some Novel Nitriles and Imidazolines Journal of Sciences, Islamic Republic of Iran |
| title | Preparation, Characterisation and Antimicrobial Activities of Some Novel Nitriles and Imidazolines |
| title_full | Preparation, Characterisation and Antimicrobial Activities of Some Novel Nitriles and Imidazolines |
| title_fullStr | Preparation, Characterisation and Antimicrobial Activities of Some Novel Nitriles and Imidazolines |
| title_full_unstemmed | Preparation, Characterisation and Antimicrobial Activities of Some Novel Nitriles and Imidazolines |
| title_short | Preparation, Characterisation and Antimicrobial Activities of Some Novel Nitriles and Imidazolines |
| title_sort | preparation characterisation and antimicrobial activities of some novel nitriles and imidazolines |
| url | https://jsciences.ut.ac.ir/article_31592_12625934005ff16320982e9f0d050eb9.pdf |