Preparation, Characterisation and Antimicrobial Activities of Some Novel Nitriles and Imidazolines
Reaction between 5-methyl-3-aminoisoxazole and ?-acetamidophenylsulpho-nylchloride yielded compound 1. Hydrolysis of compound 1 gave a starting compound 4-methoxybenzal-?-5-methyl isoxazol-3-yl-sulphonamido aniline 2. The compound 2 on condensation with different aldehydes and potassium cyanide yiel...
Saved in:
| Format: | Article |
|---|---|
| Language: | English |
| Published: |
University of Tehran
2004-06-01
|
| Series: | Journal of Sciences, Islamic Republic of Iran |
| Online Access: | https://jsciences.ut.ac.ir/article_31592_12625934005ff16320982e9f0d050eb9.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Reaction between 5-methyl-3-aminoisoxazole and ?-acetamidophenylsulpho-nylchloride yielded compound 1. Hydrolysis of compound 1 gave a starting compound 4-methoxybenzal-?-5-methyl isoxazol-3-yl-sulphonamido aniline 2. The compound 2 on condensation with different aldehydes and potassium cyanide yielded the nitriles 3a-l. Cyclocondensation between oxazolinone and compound 2 yielded imidazolines 4a-l. All compounds have been characterised using IR, 1H NMR and Mass spectral data and have been evaluated for their antimicrobial activity against different strains of bacteria and fungi. |
|---|---|
| ISSN: | 1016-1104 2345-6914 |