Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two cases
This paper reports on two cases of post-traumatic osteomyelitis (OM) caused by Aeromonas hydrophila in immunocompetent patients, a rare but severe condition. A. hydrophila, a gram-negative bacterium typically found in aquatic environments, is seldom reported as a cause of OM. The first case involved...
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| Language: | English |
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Elsevier
2025-04-01
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| Series: | Trauma Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352644025000202 |
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| author | Juan Francisco Guio Oros Estefanía Arias Cobos Juanita Villalba Reyes Jaime Andrés Leal |
| author_facet | Juan Francisco Guio Oros Estefanía Arias Cobos Juanita Villalba Reyes Jaime Andrés Leal |
| author_sort | Juan Francisco Guio Oros |
| collection | DOAJ |
| description | This paper reports on two cases of post-traumatic osteomyelitis (OM) caused by Aeromonas hydrophila in immunocompetent patients, a rare but severe condition. A. hydrophila, a gram-negative bacterium typically found in aquatic environments, is seldom reported as a cause of OM. The first case involved a 42-year-old male with a Gustilo-Anderson grade II open tibial fracture exposed to sewer water, leading to persistent infection despite initial treatment. The second case described a 38-year-old male inmate with a gunshot-induced tibial fracture managed externally, later presenting with purulent discharge and bone exposure. Both cases required extensive surgical interventions, including multiple debridements, antibiotic therapy, and bone reconstruction using distraction osteogenesis techniques. This report emphasizes the importance of early suspicion of A. hydrophila infection in patients with open fractures and water exposure, noting that standard laboratory procedures may not routinely identify this pathogen. Effective management involves a combination of surgical and medical approaches, including targeted antibiotics and aggressive surgical debridement, with some cases necessitating amputation. The rarity of this infection and its challenging treatment underscore the need for further research to develop standardized protocols and improve clinical outcomes. |
| format | Article |
| id | doaj-art-cd6710caa19b4bff9d41bffeaca81672 |
| institution | Kabale University |
| issn | 2352-6440 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Trauma Case Reports |
| spelling | doaj-art-cd6710caa19b4bff9d41bffeaca816722025-08-20T03:45:06ZengElsevierTrauma Case Reports2352-64402025-04-015610114310.1016/j.tcr.2025.101143Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two casesJuan Francisco Guio Oros0Estefanía Arias Cobos1Juanita Villalba Reyes2Jaime Andrés Leal3Orthopedics and Traumatology Resident, Hospital Universitario de la Samaritana and Pontificia Universidad Javeriana, Bogotá, ColombiaOrthopedics and Traumatology Department, Hospital Universitario de la Samaritana, Bogotá, ColombiaHospital Universitario de la Samaritana and Universidad de la Sabana, Bogotá, ColombiaOrthopedics and Traumatology Department, Hospital Universitario de la Samaritana, Bogotá, Colombia; Orthopedics and Traumatology Department, Hospital Universitario Mayor Mederi, Bogotá, Colombia; Corresponding author at: Orthopedics and Traumatology Department, Hospital Universitario de la Samaritana, Bogotá, Colombia.This paper reports on two cases of post-traumatic osteomyelitis (OM) caused by Aeromonas hydrophila in immunocompetent patients, a rare but severe condition. A. hydrophila, a gram-negative bacterium typically found in aquatic environments, is seldom reported as a cause of OM. The first case involved a 42-year-old male with a Gustilo-Anderson grade II open tibial fracture exposed to sewer water, leading to persistent infection despite initial treatment. The second case described a 38-year-old male inmate with a gunshot-induced tibial fracture managed externally, later presenting with purulent discharge and bone exposure. Both cases required extensive surgical interventions, including multiple debridements, antibiotic therapy, and bone reconstruction using distraction osteogenesis techniques. This report emphasizes the importance of early suspicion of A. hydrophila infection in patients with open fractures and water exposure, noting that standard laboratory procedures may not routinely identify this pathogen. Effective management involves a combination of surgical and medical approaches, including targeted antibiotics and aggressive surgical debridement, with some cases necessitating amputation. The rarity of this infection and its challenging treatment underscore the need for further research to develop standardized protocols and improve clinical outcomes.http://www.sciencedirect.com/science/article/pii/S2352644025000202Aeromonas hydrophilaOsteomyelitisOpen fractureLong bone defect |
| spellingShingle | Juan Francisco Guio Oros Estefanía Arias Cobos Juanita Villalba Reyes Jaime Andrés Leal Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two cases Trauma Case Reports Aeromonas hydrophila Osteomyelitis Open fracture Long bone defect |
| title | Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two cases |
| title_full | Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two cases |
| title_fullStr | Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two cases |
| title_full_unstemmed | Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two cases |
| title_short | Large bone defects in the tibia secondary to Aeromonas hydrophila infection in open fractures: Report of two cases |
| title_sort | large bone defects in the tibia secondary to aeromonas hydrophila infection in open fractures report of two cases |
| topic | Aeromonas hydrophila Osteomyelitis Open fracture Long bone defect |
| url | http://www.sciencedirect.com/science/article/pii/S2352644025000202 |
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