Burden of fungal infections in Iran

Introduction: The number of fungal infections occurring each year in Iran is not known. As the burden of fungal disease is a measure used to assess and compare the relative impact of different type of fungal diseases on populations, we have estimated the burden of fungal diseases in Iran. Method...

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Main Authors: Mohammad T Hedayati, Mojtaba Taghizadeh Armaki, Jamshid Yazdani Charati, Newsha Hedayati, Seyedmojtaba Seyedmousavi, David W Denning
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2018-10-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/10476
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author Mohammad T Hedayati
Mojtaba Taghizadeh Armaki
Jamshid Yazdani Charati
Newsha Hedayati
Seyedmojtaba Seyedmousavi
David W Denning
author_facet Mohammad T Hedayati
Mojtaba Taghizadeh Armaki
Jamshid Yazdani Charati
Newsha Hedayati
Seyedmojtaba Seyedmousavi
David W Denning
author_sort Mohammad T Hedayati
collection DOAJ
description Introduction: The number of fungal infections occurring each year in Iran is not known. As the burden of fungal disease is a measure used to assess and compare the relative impact of different type of fungal diseases on populations, we have estimated the burden of fungal diseases in Iran. Methodology: We estimated the burden of human fungal diseases based on the specific populations at risk, existing epidemiological data in both local and international databases, and modelling previously described by the LIFE program (http://www.LIFE-worldwide.org). Results: Among the population of Iran (79,926,270 in 2016), 6,670,813 (8.3%) individuals are estimated to suffer from a fungal infection each year. A total of 2,791,568 women aged between 15 and 50 years are estimated to suffer from recurrent vulvovaginal candidiasis, annually. In addition, considering the 13.3% prevalence rate of tinea capitis in children, a total of 2,552,624 cases per year are estimated. The estimated burden of invasive aspergillosis in the 3 groups of patients with hematologic malignancy, lung cancer and chronic pulmonary obstructive disease was 6394 (8.0 per 100,000). The estimate for the burden of allergic disease related to fungi including allergic bronchopulmonary aspergillosis, severe asthma with fungal sensitization and allergic fungal rhinosinusitis was 272,095 (340 per 100,000). Based on the 28,663 cases of HIV infection reported, an estimated 900 and 113 cases with pneumocystosis and cryptococcal meningitis are annually anticipated, respectively. Conclusion: Our estimates indicate that the importance of fungal infections is high but overlooked in Iran, which warrants further actions by health care authorities.
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spelling doaj-art-cd622fee0fd94c3f857ae8e40d4686072025-08-20T02:27:18ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802018-10-01121010.3855/jidc.10476Burden of fungal infections in IranMohammad T Hedayati0Mojtaba Taghizadeh Armaki1Jamshid Yazdani Charati2Newsha Hedayati3Seyedmojtaba Seyedmousavi4David W Denning5Invasive Fungi Research Center, Mazandaran University of Medical Sciences, Sari, IranBabol University of Medical Sciences, Babol, IranMazandaran University of Medical Sciences, Sari, IranMazandaran University of Medical Sciences, Sari, IranInvasive Fungi Research Center, Mazandaran University of Medical Sciences, Sari, IranThe University of Manchester, Manchester, United Kingdom Introduction: The number of fungal infections occurring each year in Iran is not known. As the burden of fungal disease is a measure used to assess and compare the relative impact of different type of fungal diseases on populations, we have estimated the burden of fungal diseases in Iran. Methodology: We estimated the burden of human fungal diseases based on the specific populations at risk, existing epidemiological data in both local and international databases, and modelling previously described by the LIFE program (http://www.LIFE-worldwide.org). Results: Among the population of Iran (79,926,270 in 2016), 6,670,813 (8.3%) individuals are estimated to suffer from a fungal infection each year. A total of 2,791,568 women aged between 15 and 50 years are estimated to suffer from recurrent vulvovaginal candidiasis, annually. In addition, considering the 13.3% prevalence rate of tinea capitis in children, a total of 2,552,624 cases per year are estimated. The estimated burden of invasive aspergillosis in the 3 groups of patients with hematologic malignancy, lung cancer and chronic pulmonary obstructive disease was 6394 (8.0 per 100,000). The estimate for the burden of allergic disease related to fungi including allergic bronchopulmonary aspergillosis, severe asthma with fungal sensitization and allergic fungal rhinosinusitis was 272,095 (340 per 100,000). Based on the 28,663 cases of HIV infection reported, an estimated 900 and 113 cases with pneumocystosis and cryptococcal meningitis are annually anticipated, respectively. Conclusion: Our estimates indicate that the importance of fungal infections is high but overlooked in Iran, which warrants further actions by health care authorities. https://jidc.org/index.php/journal/article/view/10476CandidaAspergillusvulvovaginal candidiasistinea capitisburden of fungal infectionsIran
spellingShingle Mohammad T Hedayati
Mojtaba Taghizadeh Armaki
Jamshid Yazdani Charati
Newsha Hedayati
Seyedmojtaba Seyedmousavi
David W Denning
Burden of fungal infections in Iran
Journal of Infection in Developing Countries
Candida
Aspergillus
vulvovaginal candidiasis
tinea capitis
burden of fungal infections
Iran
title Burden of fungal infections in Iran
title_full Burden of fungal infections in Iran
title_fullStr Burden of fungal infections in Iran
title_full_unstemmed Burden of fungal infections in Iran
title_short Burden of fungal infections in Iran
title_sort burden of fungal infections in iran
topic Candida
Aspergillus
vulvovaginal candidiasis
tinea capitis
burden of fungal infections
Iran
url https://jidc.org/index.php/journal/article/view/10476
work_keys_str_mv AT mohammadthedayati burdenoffungalinfectionsiniran
AT mojtabataghizadeharmaki burdenoffungalinfectionsiniran
AT jamshidyazdanicharati burdenoffungalinfectionsiniran
AT newshahedayati burdenoffungalinfectionsiniran
AT seyedmojtabaseyedmousavi burdenoffungalinfectionsiniran
AT davidwdenning burdenoffungalinfectionsiniran