Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals
The study of acute toxicity and allergenity glycopeptides lactic acid bacteria in mice and rabbits. At the present level of physical, chemical and biological pollution of the environment, domestic and farm animals in no less, if not more than people, suffer from secondary induced immunodeficiency -...
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| Format: | Article |
| Language: | Russian |
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LLC “Publisher OKI”
2019-02-01
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| Series: | Фармакокинетика и Фармакодинамика |
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| Online Access: | https://www.pharmacokinetica.ru/jour/article/view/96 |
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| author | O. V. Sofronova L. L. Polyakova A. N. Ovcharova |
| author_facet | O. V. Sofronova L. L. Polyakova A. N. Ovcharova |
| author_sort | O. V. Sofronova |
| collection | DOAJ |
| description | The study of acute toxicity and allergenity glycopeptides lactic acid bacteria in mice and rabbits. At the present level of physical, chemical and biological pollution of the environment, domestic and farm animals in no less, if not more than people, suffer from secondary induced immunodeficiency - an imbalance in the normal functioning of the immune system. This leads to a significant reduction in the overall resistance of the animal to various diseases of a viral and bacterial nature. The normal functioning of the animal's immune system can be restored with the help of immunomodulators, the active principle of which is the glycopeptide synthesized from natural components - a universal structural fragment of the lactic acid bacteria cell membrane that interacts with the immune system of the animal organism. |
| format | Article |
| id | doaj-art-cd5f91e00a7e463bb6493775b9a96776 |
| institution | Kabale University |
| issn | 2587-7836 2686-8830 |
| language | Russian |
| publishDate | 2019-02-01 |
| publisher | LLC “Publisher OKI” |
| record_format | Article |
| series | Фармакокинетика и Фармакодинамика |
| spelling | doaj-art-cd5f91e00a7e463bb6493775b9a967762025-08-20T03:57:48ZrusLLC “Publisher OKI”Фармакокинетика и Фармакодинамика2587-78362686-88302019-02-0102596310.24411/2587-7836-2019-1004995Determination of the safety of glycopeptides lactic acid bacteria in laboratory animalsO. V. Sofronova0L. L. Polyakova1A. N. Ovcharova2All-Russian Research Institute of Physiology, Biochemistry and Nutrition of animals - branch of Federal state budgetary scientific institution "Federal Research Center Livestock - AUIAB Academician LK Ernst"All-Russian Research Institute of Physiology, Biochemistry and Nutrition of animals - branch of Federal state budgetary scientific institution "Federal Research Center Livestock - AUIAB Academician LK Ernst"All-Russian Research Institute of Physiology, Biochemistry and Nutrition of animals - branch of Federal state budgetary scientific institution "Federal Research Center Livestock - AUIAB Academician LK Ernst"The study of acute toxicity and allergenity glycopeptides lactic acid bacteria in mice and rabbits. At the present level of physical, chemical and biological pollution of the environment, domestic and farm animals in no less, if not more than people, suffer from secondary induced immunodeficiency - an imbalance in the normal functioning of the immune system. This leads to a significant reduction in the overall resistance of the animal to various diseases of a viral and bacterial nature. The normal functioning of the animal's immune system can be restored with the help of immunomodulators, the active principle of which is the glycopeptide synthesized from natural components - a universal structural fragment of the lactic acid bacteria cell membrane that interacts with the immune system of the animal organism.https://www.pharmacokinetica.ru/jour/article/view/96гликопептидымолочнокислые бактериисреднесмертельная дозатоксичность и аллергенностьglycopeptideslactic acid bacteriaтне medium lethal dosetoxicity and allergenicity |
| spellingShingle | O. V. Sofronova L. L. Polyakova A. N. Ovcharova Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals Фармакокинетика и Фармакодинамика гликопептиды молочнокислые бактерии среднесмертельная доза токсичность и аллергенность glycopeptides lactic acid bacteria тне medium lethal dose toxicity and allergenicity |
| title | Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals |
| title_full | Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals |
| title_fullStr | Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals |
| title_full_unstemmed | Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals |
| title_short | Determination of the safety of glycopeptides lactic acid bacteria in laboratory animals |
| title_sort | determination of the safety of glycopeptides lactic acid bacteria in laboratory animals |
| topic | гликопептиды молочнокислые бактерии среднесмертельная доза токсичность и аллергенность glycopeptides lactic acid bacteria тне medium lethal dose toxicity and allergenicity |
| url | https://www.pharmacokinetica.ru/jour/article/view/96 |
| work_keys_str_mv | AT ovsofronova determinationofthesafetyofglycopeptideslacticacidbacteriainlaboratoryanimals AT llpolyakova determinationofthesafetyofglycopeptideslacticacidbacteriainlaboratoryanimals AT anovcharova determinationofthesafetyofglycopeptideslacticacidbacteriainlaboratoryanimals |