Clinical Characteristics of Nocardia Infection in Patients with Rheumatic Diseases

Although Nocardiosis has considerable recurrence and mortality rates, characteristics and risk factors of Nocardia infection have not been assessed in patients with rheumatic diseases. Here, we examined the characteristics and risk factors of Nocardia infection in rheumatic disease patients in our h...

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Main Authors: Mieko Yamagata, Koichi Hirose, Kei Ikeda, Hiroshi Nakajima
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2013/818654
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author Mieko Yamagata
Koichi Hirose
Kei Ikeda
Hiroshi Nakajima
author_facet Mieko Yamagata
Koichi Hirose
Kei Ikeda
Hiroshi Nakajima
author_sort Mieko Yamagata
collection DOAJ
description Although Nocardiosis has considerable recurrence and mortality rates, characteristics and risk factors of Nocardia infection have not been assessed in patients with rheumatic diseases. Here, we examined the characteristics and risk factors of Nocardia infection in rheumatic disease patients in our hospital. Ten rheumatic disease patients who developed Nocardia infection were identified by retrospectively reviewing the medical records. Possible predisposing factors for Nocardia infection were high-dose glucocorticoid treatment, concomitant use of immunosuppressants, preexisting pulmonary diseases, and diabetes mellitus. All patients had pulmonary Nocardiosis, and six of them had disseminated Nocardiosis when their pulmonary lesions were identified.
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spelling doaj-art-cd5f2e2619e04512bdf1bfd43c98dd7a2025-08-20T02:19:51ZengWileyClinical and Developmental Immunology1740-25221740-25302013-01-01201310.1155/2013/818654818654Clinical Characteristics of Nocardia Infection in Patients with Rheumatic DiseasesMieko Yamagata0Koichi Hirose1Kei Ikeda2Hiroshi Nakajima3Department of Allergy and Clinical Immunology, Chiba University Hospital, 1-8-1 Inohana, Chiba, Chiba City 260-8677, JapanDepartment of Allergy and Clinical Immunology, Chiba University Hospital, 1-8-1 Inohana, Chiba, Chiba City 260-8677, JapanDepartment of Allergy and Clinical Immunology, Chiba University Hospital, 1-8-1 Inohana, Chiba, Chiba City 260-8677, JapanDepartment of Allergy and Clinical Immunology, Chiba University Hospital, 1-8-1 Inohana, Chiba, Chiba City 260-8677, JapanAlthough Nocardiosis has considerable recurrence and mortality rates, characteristics and risk factors of Nocardia infection have not been assessed in patients with rheumatic diseases. Here, we examined the characteristics and risk factors of Nocardia infection in rheumatic disease patients in our hospital. Ten rheumatic disease patients who developed Nocardia infection were identified by retrospectively reviewing the medical records. Possible predisposing factors for Nocardia infection were high-dose glucocorticoid treatment, concomitant use of immunosuppressants, preexisting pulmonary diseases, and diabetes mellitus. All patients had pulmonary Nocardiosis, and six of them had disseminated Nocardiosis when their pulmonary lesions were identified.http://dx.doi.org/10.1155/2013/818654
spellingShingle Mieko Yamagata
Koichi Hirose
Kei Ikeda
Hiroshi Nakajima
Clinical Characteristics of Nocardia Infection in Patients with Rheumatic Diseases
Clinical and Developmental Immunology
title Clinical Characteristics of Nocardia Infection in Patients with Rheumatic Diseases
title_full Clinical Characteristics of Nocardia Infection in Patients with Rheumatic Diseases
title_fullStr Clinical Characteristics of Nocardia Infection in Patients with Rheumatic Diseases
title_full_unstemmed Clinical Characteristics of Nocardia Infection in Patients with Rheumatic Diseases
title_short Clinical Characteristics of Nocardia Infection in Patients with Rheumatic Diseases
title_sort clinical characteristics of nocardia infection in patients with rheumatic diseases
url http://dx.doi.org/10.1155/2013/818654
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