Epidemiology and outcomes of respiratory distress in newborns

Respiratory distress of newborns is one of the most frequent causes of infant admission to intensive care units, the development of severe complications of the neonatal period and lethal outcomes.The objective was to study the epidemiology and outcomes of respiratory distress in newborns requiring i...

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Main Authors: Yu. S. Aleksandrovich, J. A. Temirova, S. V. Vasiliev, I. V. Boronina, Yu. V. Bykov
Format: Article
Language:Russian
Published: New Terra Publishing House 2023-06-01
Series:Вестник анестезиологии и реаниматологии
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Online Access:https://www.vair-journal.com/jour/article/view/818
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author Yu. S. Aleksandrovich
J. A. Temirova
S. V. Vasiliev
I. V. Boronina
Yu. V. Bykov
author_facet Yu. S. Aleksandrovich
J. A. Temirova
S. V. Vasiliev
I. V. Boronina
Yu. V. Bykov
author_sort Yu. S. Aleksandrovich
collection DOAJ
description Respiratory distress of newborns is one of the most frequent causes of infant admission to intensive care units, the development of severe complications of the neonatal period and lethal outcomes.The objective was to study the epidemiology and outcomes of respiratory distress in newborns requiring intensive care measures.Materials and methods. The design was a retrospective observational study. We examined 180 newborns, the mean weight was 1620 (1075–2197.5) g, and the gestational age was 31.8 (29–34.5) weeks. Apgar score at minute 1 was 5 (4–7) and at minute 5 was 7 (6–7) scores. The duration of artificial lung ventilation was 2 (12.5–242) hours, and the duration of treatment in the NICU was 10 (6–19) days. Lethal outcomes occurred in 6 (3%) cases.Results. The most frequent cause of respiratory distress in newborns was respiratory distress syndrome in newborns (53%). The second place was occupied by asphyxia in childbirth (31%). Intra-amniotic infection was detected in 11 (6%) newborns, and intrauterine pneumonia in 5 (3%) infants. Transient tachypnea was registered in 6 (3%) newborns, and meconium aspiration syndrome – in 8 (4%) patients. In premature infants, the most severe course of respiratory distress was noted in pneumonia and asphyxia, in mature infants – in meconium aspiration syndrome. The maximum duration of intensive care measures was observed in intra-amniotic infection – 16 days and respiratory distress syndrome – 11 days. The outcome in 47% was favorable – complete recovery. Unfavorable outcomes included intraventricular hemorrhage (12%), combination of two or more complications (20%), bronchopulmonary dysplasia (5%), and persistent arterial ductus (4%).Conclusion. The outcome of respiratory distress in newborns with adequate assessment of the severity of the condition and timely initiated evidence-based treatment is determined not by the main clinical diagnosis, but by the gestational age and severity of the infant condition at the time of birth.
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spelling doaj-art-cd5a9c7cbd7246d1a746a0e9582385402025-08-20T02:59:42ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532023-06-01203758310.24884/2078-5658-2023-20-3-75-83607Epidemiology and outcomes of respiratory distress in newbornsYu. S. Aleksandrovich0J. A. Temirova1S. V. Vasiliev2I. V. Boronina3Yu. V. Bykov4Saint-Petersburg State Pediatric Medical UniversityLeningrad Regional Clinical HospitalExpert Legal Center LLCVoronezh State Medical UniversityStavropol State Medical UniversityRespiratory distress of newborns is one of the most frequent causes of infant admission to intensive care units, the development of severe complications of the neonatal period and lethal outcomes.The objective was to study the epidemiology and outcomes of respiratory distress in newborns requiring intensive care measures.Materials and methods. The design was a retrospective observational study. We examined 180 newborns, the mean weight was 1620 (1075–2197.5) g, and the gestational age was 31.8 (29–34.5) weeks. Apgar score at minute 1 was 5 (4–7) and at minute 5 was 7 (6–7) scores. The duration of artificial lung ventilation was 2 (12.5–242) hours, and the duration of treatment in the NICU was 10 (6–19) days. Lethal outcomes occurred in 6 (3%) cases.Results. The most frequent cause of respiratory distress in newborns was respiratory distress syndrome in newborns (53%). The second place was occupied by asphyxia in childbirth (31%). Intra-amniotic infection was detected in 11 (6%) newborns, and intrauterine pneumonia in 5 (3%) infants. Transient tachypnea was registered in 6 (3%) newborns, and meconium aspiration syndrome – in 8 (4%) patients. In premature infants, the most severe course of respiratory distress was noted in pneumonia and asphyxia, in mature infants – in meconium aspiration syndrome. The maximum duration of intensive care measures was observed in intra-amniotic infection – 16 days and respiratory distress syndrome – 11 days. The outcome in 47% was favorable – complete recovery. Unfavorable outcomes included intraventricular hemorrhage (12%), combination of two or more complications (20%), bronchopulmonary dysplasia (5%), and persistent arterial ductus (4%).Conclusion. The outcome of respiratory distress in newborns with adequate assessment of the severity of the condition and timely initiated evidence-based treatment is determined not by the main clinical diagnosis, but by the gestational age and severity of the infant condition at the time of birth.https://www.vair-journal.com/jour/article/view/818respiratory distressnewbornsrespiratory supportfavorable outcomeunfavorable outcome
spellingShingle Yu. S. Aleksandrovich
J. A. Temirova
S. V. Vasiliev
I. V. Boronina
Yu. V. Bykov
Epidemiology and outcomes of respiratory distress in newborns
Вестник анестезиологии и реаниматологии
respiratory distress
newborns
respiratory support
favorable outcome
unfavorable outcome
title Epidemiology and outcomes of respiratory distress in newborns
title_full Epidemiology and outcomes of respiratory distress in newborns
title_fullStr Epidemiology and outcomes of respiratory distress in newborns
title_full_unstemmed Epidemiology and outcomes of respiratory distress in newborns
title_short Epidemiology and outcomes of respiratory distress in newborns
title_sort epidemiology and outcomes of respiratory distress in newborns
topic respiratory distress
newborns
respiratory support
favorable outcome
unfavorable outcome
url https://www.vair-journal.com/jour/article/view/818
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AT svvasiliev epidemiologyandoutcomesofrespiratorydistressinnewborns
AT ivboronina epidemiologyandoutcomesofrespiratorydistressinnewborns
AT yuvbykov epidemiologyandoutcomesofrespiratorydistressinnewborns