Association between Serum Zinc Level and Cutaneous Viral Warts: A Case Control Study

Introduction: Cutaneous viral warts are one of the common skin disorders in general population which can affect any age group and any gender in any country and pose a significant health problem. A possible association with zinc has been suggested in previous studies. Zinc is known to be required fo...

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Main Authors: Annu Ranjit, Sudharshan Lal Rajbhandari, Narayan Gautam, Yogesh Poudyal
Format: Article
Language:English
Published: Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) 2019-03-01
Series:Nepal Journal of Dermatology, Venereology & Leprology
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Online Access:https://nepjol.info/index.php/NJDVL/article/view/23153
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author Annu Ranjit
Sudharshan Lal Rajbhandari
Narayan Gautam
Yogesh Poudyal
author_facet Annu Ranjit
Sudharshan Lal Rajbhandari
Narayan Gautam
Yogesh Poudyal
author_sort Annu Ranjit
collection DOAJ
description Introduction: Cutaneous viral warts are one of the common skin disorders in general population which can affect any age group and any gender in any country and pose a significant health problem. A possible association with zinc has been suggested in previous studies. Zinc is known to be required for efficient functioning of immune system. Objective: To find out the association between serum zinc level and cutaneous viral warts.  Materials and methods: In this case-control study, total of hundred patients were enrolled. Among them 50 (males – 27, females – 23) with cutaneous viral warts were taken as cases and 50 (males – 25, females – 25) healthy individuals were taken as controls after matching the age and sex. The patients were selected from Dermatology outpatient Department of Universal College of Medical Sciences Teaching Hospital, Bhairahawa, Nepal. The serum zinc level was measured using spectrophotometry principle. Results: The mean serum zinc level in the cases and controls were 80.50±37.24 mg/dl and 104.31±25.31 mg/dl respectively. Significant difference in serum zinc level was observed between cases and controls (p=0.0001). There was a strong association between low serum zinc level and cutaneous viral warts (OR=7.37; 95% CI=1.98 – 27.31; p=0.0028). Conclusion: Serum zinc level in patients with cutaneous viral warts was significantly low as compared to the healthy controls.
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publishDate 2019-03-01
publisher Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
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spelling doaj-art-cd49abb6db2e4065a557d9fa2b9fbe6b2025-08-24T10:06:18ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2019-03-01171Association between Serum Zinc Level and Cutaneous Viral Warts: A Case Control StudyAnnu Ranjit0Sudharshan Lal Rajbhandari1Narayan Gautam2Yogesh Poudyal3Gandaki Medical College, pokhara, NepalNAIHS College of Medicine, KathmanduUniversal College of Medical Sciences, BhairahawaSarnath Skin Centre, Bhairahawa Introduction: Cutaneous viral warts are one of the common skin disorders in general population which can affect any age group and any gender in any country and pose a significant health problem. A possible association with zinc has been suggested in previous studies. Zinc is known to be required for efficient functioning of immune system. Objective: To find out the association between serum zinc level and cutaneous viral warts.  Materials and methods: In this case-control study, total of hundred patients were enrolled. Among them 50 (males – 27, females – 23) with cutaneous viral warts were taken as cases and 50 (males – 25, females – 25) healthy individuals were taken as controls after matching the age and sex. The patients were selected from Dermatology outpatient Department of Universal College of Medical Sciences Teaching Hospital, Bhairahawa, Nepal. The serum zinc level was measured using spectrophotometry principle. Results: The mean serum zinc level in the cases and controls were 80.50±37.24 mg/dl and 104.31±25.31 mg/dl respectively. Significant difference in serum zinc level was observed between cases and controls (p=0.0001). There was a strong association between low serum zinc level and cutaneous viral warts (OR=7.37; 95% CI=1.98 – 27.31; p=0.0028). Conclusion: Serum zinc level in patients with cutaneous viral warts was significantly low as compared to the healthy controls. https://nepjol.info/index.php/NJDVL/article/view/23153Immune systemmicronutrientspapillomaviridaewartszinc
spellingShingle Annu Ranjit
Sudharshan Lal Rajbhandari
Narayan Gautam
Yogesh Poudyal
Association between Serum Zinc Level and Cutaneous Viral Warts: A Case Control Study
Nepal Journal of Dermatology, Venereology & Leprology
Immune system
micronutrients
papillomaviridae
warts
zinc
title Association between Serum Zinc Level and Cutaneous Viral Warts: A Case Control Study
title_full Association between Serum Zinc Level and Cutaneous Viral Warts: A Case Control Study
title_fullStr Association between Serum Zinc Level and Cutaneous Viral Warts: A Case Control Study
title_full_unstemmed Association between Serum Zinc Level and Cutaneous Viral Warts: A Case Control Study
title_short Association between Serum Zinc Level and Cutaneous Viral Warts: A Case Control Study
title_sort association between serum zinc level and cutaneous viral warts a case control study
topic Immune system
micronutrients
papillomaviridae
warts
zinc
url https://nepjol.info/index.php/NJDVL/article/view/23153
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