Peritoneal adipose stem cell-derived extracellular vesicles mediate the regulation of ovarian cancer cell proliferation and migration through EGFR-NF-κB signaling

Peritoneal adipose stem cell-derived extracellular vesicles mediate the regulation of ovarian cancer cell proliferation and migration through EGFR-NF-κB signaling

Peritoneal dissemination frequently develops in patients with ovarian cancer (OC) and is associated with recurrence and metastasis. However, the cellular components and mechanisms supporting OC peritoneal metastasis are poorly understood. To elucidate these, we utilized RNA sequencing to investigate...

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Bibliographic Details
Main Authors: Lian Wang, Ning Luo, Jihui Zhu, Zubaidan Sulaiman, Wenhan Yang, Ke Hu, Guihai Ai, Weihong Yang, Xiaowen Shao, Shengkai Jin, Xue Zhang, Yantao Fan, Dan Deng, Zhongping Cheng, Zhengliang Gao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Genes and Diseases
Subjects:
Adipose-derived stem cells
EGFR/NK-κB axis
Extracellular vesicles
Metastasis
Ovarian cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304224000801
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