The Potential Regulators of Amyloidogenic Pathway of APP Processing in Alzheimer’s Disease
The amyloidogenic processing of amyloid precursor protein (APP) plays a pivotal role in the pathogenesis of Alzheimer’s disease (AD), primarily through the generation of amyloid-beta (Aβ) peptides, which aggregate to form toxic plaques in the brain. The regulation of amyloidogenic APP processing is...
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| Main Authors: | Daria Krawczuk, Agnieszka Kulczyńska-Przybik, Barbara Mroczko |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
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| Series: | Biomedicines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9059/13/7/1513 |
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