Development and validation of a Delphi consensus-based questionnaire for the multidisciplinary management of type 2 inflammation-related diseases
ObjectiveThis study aimed to validate a 15-item screening questionnaire for the early detection of coexisting type 2 (T2) inflammatory diseases, such as asthma, atopic dermatitis, and chronic rhinosinusitis with nasal polyps (CRSwNP), among others.MethodsThe questionnaire, designed through expert co...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
|
| Series: | Frontiers in Allergy |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/falgy.2025.1543504/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850262266707968000 |
|---|---|
| author | Francisco Javier Ortiz de Frutos Carolina Cisneros José Miguel Villacampa Óscar Palomares Ignacio Dávila |
| author_facet | Francisco Javier Ortiz de Frutos Carolina Cisneros José Miguel Villacampa Óscar Palomares Ignacio Dávila |
| author_sort | Francisco Javier Ortiz de Frutos |
| collection | DOAJ |
| description | ObjectiveThis study aimed to validate a 15-item screening questionnaire for the early detection of coexisting type 2 (T2) inflammatory diseases, such as asthma, atopic dermatitis, and chronic rhinosinusitis with nasal polyps (CRSwNP), among others.MethodsThe questionnaire, designed through expert consensus by a scientific committee, underwent Delphi methodology for validation. A multidisciplinary panel of 19 clinicians from different specialties reviewed the questionnaire for clinical relevance, while 39 patients from different regions of Spain evaluated its comprehensibility.ResultsThe clinician panel reached a consensus on the relevance of 13 out of 15 items in the first round and agreed that a single positive response was sufficient to justify referral to the appropriate specialist. Two items were modified and validated in the second round. The patient panel unanimously agreed on the comprehensibility of the questionnaire in the first round. Linguistic variations were also ranked to ensure clarity across regions, further enhancing the validation of the tool.ConclusionThis validated questionnaire offers a practical tool for early detection of T2 inflammatory diseases. Its simplicity and comprehensibility, confirmed by clinicians and patients, make it suitable for use in various healthcare settings, supporting timely specialist referrals and improved patient care. Future studies will evaluate its effectiveness in real-world clinical practice. |
| format | Article |
| id | doaj-art-cd3073cf3f824d3d850a03bfee278357 |
| institution | OA Journals |
| issn | 2673-6101 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Allergy |
| spelling | doaj-art-cd3073cf3f824d3d850a03bfee2783572025-08-20T01:55:12ZengFrontiers Media S.A.Frontiers in Allergy2673-61012025-04-01610.3389/falgy.2025.15435041543504Development and validation of a Delphi consensus-based questionnaire for the multidisciplinary management of type 2 inflammation-related diseasesFrancisco Javier Ortiz de Frutos0Carolina Cisneros1José Miguel Villacampa2Óscar Palomares3Ignacio Dávila4Dermatology Department, University Hospital 12 de Octubre, Madrid, SpainPneumology Department, La Princesa Hospital, Madrid, SpainENT Department, Fundación Jiménez Díaz University Hospital, Madrid, SpainDepartment of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Madrid, SpainAllergy Service, University Hospital of Salamanca, Red de Enfermedades Inflamatorias, ISCIII, Departamento de Ciencias Biomédicas y del Diagnóstico, Instituto de Investigación Biosanitaria de Salamanca, Salamanca, SpainObjectiveThis study aimed to validate a 15-item screening questionnaire for the early detection of coexisting type 2 (T2) inflammatory diseases, such as asthma, atopic dermatitis, and chronic rhinosinusitis with nasal polyps (CRSwNP), among others.MethodsThe questionnaire, designed through expert consensus by a scientific committee, underwent Delphi methodology for validation. A multidisciplinary panel of 19 clinicians from different specialties reviewed the questionnaire for clinical relevance, while 39 patients from different regions of Spain evaluated its comprehensibility.ResultsThe clinician panel reached a consensus on the relevance of 13 out of 15 items in the first round and agreed that a single positive response was sufficient to justify referral to the appropriate specialist. Two items were modified and validated in the second round. The patient panel unanimously agreed on the comprehensibility of the questionnaire in the first round. Linguistic variations were also ranked to ensure clarity across regions, further enhancing the validation of the tool.ConclusionThis validated questionnaire offers a practical tool for early detection of T2 inflammatory diseases. Its simplicity and comprehensibility, confirmed by clinicians and patients, make it suitable for use in various healthcare settings, supporting timely specialist referrals and improved patient care. Future studies will evaluate its effectiveness in real-world clinical practice.https://www.frontiersin.org/articles/10.3389/falgy.2025.1543504/fullT2 inflammationmanagementmultidisciplinaryscreeningquestionnaire |
| spellingShingle | Francisco Javier Ortiz de Frutos Carolina Cisneros José Miguel Villacampa Óscar Palomares Ignacio Dávila Development and validation of a Delphi consensus-based questionnaire for the multidisciplinary management of type 2 inflammation-related diseases Frontiers in Allergy T2 inflammation management multidisciplinary screening questionnaire |
| title | Development and validation of a Delphi consensus-based questionnaire for the multidisciplinary management of type 2 inflammation-related diseases |
| title_full | Development and validation of a Delphi consensus-based questionnaire for the multidisciplinary management of type 2 inflammation-related diseases |
| title_fullStr | Development and validation of a Delphi consensus-based questionnaire for the multidisciplinary management of type 2 inflammation-related diseases |
| title_full_unstemmed | Development and validation of a Delphi consensus-based questionnaire for the multidisciplinary management of type 2 inflammation-related diseases |
| title_short | Development and validation of a Delphi consensus-based questionnaire for the multidisciplinary management of type 2 inflammation-related diseases |
| title_sort | development and validation of a delphi consensus based questionnaire for the multidisciplinary management of type 2 inflammation related diseases |
| topic | T2 inflammation management multidisciplinary screening questionnaire |
| url | https://www.frontiersin.org/articles/10.3389/falgy.2025.1543504/full |
| work_keys_str_mv | AT franciscojavierortizdefrutos developmentandvalidationofadelphiconsensusbasedquestionnaireforthemultidisciplinarymanagementoftype2inflammationrelateddiseases AT carolinacisneros developmentandvalidationofadelphiconsensusbasedquestionnaireforthemultidisciplinarymanagementoftype2inflammationrelateddiseases AT josemiguelvillacampa developmentandvalidationofadelphiconsensusbasedquestionnaireforthemultidisciplinarymanagementoftype2inflammationrelateddiseases AT oscarpalomares developmentandvalidationofadelphiconsensusbasedquestionnaireforthemultidisciplinarymanagementoftype2inflammationrelateddiseases AT ignaciodavila developmentandvalidationofadelphiconsensusbasedquestionnaireforthemultidisciplinarymanagementoftype2inflammationrelateddiseases |