Blind peroneal artery outflow bypass for limb salvage in patients with severe CLTI: A case series

Objective: Limb loss carries a high risk of morbidity and mortality in patients with chronic limb-threatening ischemia (CLTI). Multiple medical and surgical strategies have been studied to address complications and lower amputation rates, especially in patients with poor outflow in the infragenicula...

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Main Authors: Jorge Rey, MD, Karen Manzur-Pineda, MD, Christopher Montoya, MD, Stefan Kenel-Pierre, MD, Naixin Kang, MD, Kathy Gonzalez, MD, Arash Bornak, MD
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Annals of Vascular Surgery - Brief Reports and Innovations
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772687824000941
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author Jorge Rey, MD
Karen Manzur-Pineda, MD
Christopher Montoya, MD
Stefan Kenel-Pierre, MD
Naixin Kang, MD
Kathy Gonzalez, MD
Arash Bornak, MD
author_facet Jorge Rey, MD
Karen Manzur-Pineda, MD
Christopher Montoya, MD
Stefan Kenel-Pierre, MD
Naixin Kang, MD
Kathy Gonzalez, MD
Arash Bornak, MD
author_sort Jorge Rey, MD
collection DOAJ
description Objective: Limb loss carries a high risk of morbidity and mortality in patients with chronic limb-threatening ischemia (CLTI). Multiple medical and surgical strategies have been studied to address complications and lower amputation rates, especially in patients with poor outflow in the infrageniculate arteries. Our case series highlights the use of the peroneal bypass without angiographic runoff but acceptable intraoperative back-bleed as an option for patients with CLTI. Methods: A single-center retrospective review was performed on adult patients who underwent lower extremity bypass using the peroneal artery as the outflow for CLTI from 2012 to 2022. Two subgroups were classified as blind peroneal arteries and non-blind peroneal arteries, according to the Darling et al.'s 1998 classification. Results: A total of twenty-five patients with lower extremity bypass for CLTI with the peroneal artery as the outflow target were included. From those, seventeen were classified as non-blind and eight were defined as blind peroneal, according to preoperative angiography runoff. Blind peroneal bypass primary patency rate was 45%, primary-assisted was 60%, and secondary was 60%, with a limb loss rate of 25.0%. Among the seventeen non-blind peroneal bypasses, primary patency was 64.5%, primary assisted was 77%, and secondary was 77%, with a limb loss rate of 5.9%. There were no significantly different p-values observed between both groups. Conclusion: Blind peroneal bypasses serve as a last resort strategy to attempt limb salvage before amputation if adequate back-bleed is observed intraoperatively.
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spelling doaj-art-cd2c752ef47d4ddda9110edcc2d36e452025-08-20T02:34:20ZengElsevierAnnals of Vascular Surgery - Brief Reports and Innovations2772-68782024-12-014410034210.1016/j.avsurg.2024.100342Blind peroneal artery outflow bypass for limb salvage in patients with severe CLTI: A case seriesJorge Rey, MD0Karen Manzur-Pineda, MD1Christopher Montoya, MD2Stefan Kenel-Pierre, MD3Naixin Kang, MD4Kathy Gonzalez, MD5Arash Bornak, MD6Corresponding author: Division Chief, Department of Vascular and Endovascular Surgery., DeWitt Daughtry Family Department of Surgery, Division of Vascular and Endovascular Department. Leonard M. Miller School of Medicine, University of Miami, Miami, FL. Miami, FL. 33136.; DeWitt Daughtry Family Department of Surgery, Division of Vascular Surgery, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USADeWitt Daughtry Family Department of Surgery, Division of Vascular Surgery, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USADeWitt Daughtry Family Department of Surgery, Division of Vascular Surgery, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USADeWitt Daughtry Family Department of Surgery, Division of Vascular Surgery, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USADeWitt Daughtry Family Department of Surgery, Division of Vascular Surgery, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USADeWitt Daughtry Family Department of Surgery, Division of Vascular Surgery, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USADeWitt Daughtry Family Department of Surgery, Division of Vascular Surgery, University of Miami, Leonard M. Miller School of Medicine, Miami, FL, USAObjective: Limb loss carries a high risk of morbidity and mortality in patients with chronic limb-threatening ischemia (CLTI). Multiple medical and surgical strategies have been studied to address complications and lower amputation rates, especially in patients with poor outflow in the infrageniculate arteries. Our case series highlights the use of the peroneal bypass without angiographic runoff but acceptable intraoperative back-bleed as an option for patients with CLTI. Methods: A single-center retrospective review was performed on adult patients who underwent lower extremity bypass using the peroneal artery as the outflow for CLTI from 2012 to 2022. Two subgroups were classified as blind peroneal arteries and non-blind peroneal arteries, according to the Darling et al.'s 1998 classification. Results: A total of twenty-five patients with lower extremity bypass for CLTI with the peroneal artery as the outflow target were included. From those, seventeen were classified as non-blind and eight were defined as blind peroneal, according to preoperative angiography runoff. Blind peroneal bypass primary patency rate was 45%, primary-assisted was 60%, and secondary was 60%, with a limb loss rate of 25.0%. Among the seventeen non-blind peroneal bypasses, primary patency was 64.5%, primary assisted was 77%, and secondary was 77%, with a limb loss rate of 5.9%. There were no significantly different p-values observed between both groups. Conclusion: Blind peroneal bypasses serve as a last resort strategy to attempt limb salvage before amputation if adequate back-bleed is observed intraoperatively.http://www.sciencedirect.com/science/article/pii/S2772687824000941Arterial bypassChronic limb ischemiaLower extremity revascularizationLimb salvagePeroneal artery outflow
spellingShingle Jorge Rey, MD
Karen Manzur-Pineda, MD
Christopher Montoya, MD
Stefan Kenel-Pierre, MD
Naixin Kang, MD
Kathy Gonzalez, MD
Arash Bornak, MD
Blind peroneal artery outflow bypass for limb salvage in patients with severe CLTI: A case series
Annals of Vascular Surgery - Brief Reports and Innovations
Arterial bypass
Chronic limb ischemia
Lower extremity revascularization
Limb salvage
Peroneal artery outflow
title Blind peroneal artery outflow bypass for limb salvage in patients with severe CLTI: A case series
title_full Blind peroneal artery outflow bypass for limb salvage in patients with severe CLTI: A case series
title_fullStr Blind peroneal artery outflow bypass for limb salvage in patients with severe CLTI: A case series
title_full_unstemmed Blind peroneal artery outflow bypass for limb salvage in patients with severe CLTI: A case series
title_short Blind peroneal artery outflow bypass for limb salvage in patients with severe CLTI: A case series
title_sort blind peroneal artery outflow bypass for limb salvage in patients with severe clti a case series
topic Arterial bypass
Chronic limb ischemia
Lower extremity revascularization
Limb salvage
Peroneal artery outflow
url http://www.sciencedirect.com/science/article/pii/S2772687824000941
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