Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis

Abstract Background Venous thrombosis is a common complication after hip arthroplasty. Methods PubMed, Embase, the Cochrane Library, and Web of Science were searched for case-control studies on risk factors for venous thrombosis after hip arthroplasty up to September 14, 2023. Data analysis was perf...

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Main Authors: Wang Huang, Weiwei Hu, Bangguo Lei, Weichen Huang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Musculoskeletal Disorders
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Online Access:https://doi.org/10.1186/s12891-025-08764-z
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author Wang Huang
Weiwei Hu
Bangguo Lei
Weichen Huang
author_facet Wang Huang
Weiwei Hu
Bangguo Lei
Weichen Huang
author_sort Wang Huang
collection DOAJ
description Abstract Background Venous thrombosis is a common complication after hip arthroplasty. Methods PubMed, Embase, the Cochrane Library, and Web of Science were searched for case-control studies on risk factors for venous thrombosis after hip arthroplasty up to September 14, 2023. Data analysis was performed using Stata15.0. Results This meta-analysis included 15 case-control studies, comprising 17,909 participants, including 1149 patients with venous thrombosis and 16,760 patients without venous thrombosis. The univariate meta-analysis results revealed that age over 70 years old, hypertension, BMI ≥ 25, operation time, stroke, and use of mechanical prophylaxis alone were risk factors for venous thrombosis after hip arthroplasty. Multivariate analysis showed that female, age > 70 years, BMI ≥ 25, cemented prosthesis, and a history of venous thrombosis were the risk factors for venous thrombosis after hip arthroplasty. Conclusions This study suggests that female sex, age over 70 years, hypertension, a BMI of 25 or higher, duration of operation, stroke, mechanical prevention only, use of a cemented prosthesis, and a history of venous thrombosis are risk factors for venous thrombosis following hip arthroplasty. Clinical trial number not applicable.
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spelling doaj-art-cd2bf84e791c49d7be119f48d460e6722025-08-20T03:48:18ZengBMCBMC Musculoskeletal Disorders1471-24742025-05-0126111010.1186/s12891-025-08764-zRisk factors for venous thrombosis after hip arthroplasty: a meta-analysisWang Huang0Weiwei Hu1Bangguo Lei2Weichen Huang3Guizhou University of Traditional Chinese MedicineGuizhou University of Traditional Chinese MedicineGuizhou University of Traditional Chinese MedicineThe Second Affiliated Hospital of Guizhou, University of Traditional Chinese MedicineAbstract Background Venous thrombosis is a common complication after hip arthroplasty. Methods PubMed, Embase, the Cochrane Library, and Web of Science were searched for case-control studies on risk factors for venous thrombosis after hip arthroplasty up to September 14, 2023. Data analysis was performed using Stata15.0. Results This meta-analysis included 15 case-control studies, comprising 17,909 participants, including 1149 patients with venous thrombosis and 16,760 patients without venous thrombosis. The univariate meta-analysis results revealed that age over 70 years old, hypertension, BMI ≥ 25, operation time, stroke, and use of mechanical prophylaxis alone were risk factors for venous thrombosis after hip arthroplasty. Multivariate analysis showed that female, age > 70 years, BMI ≥ 25, cemented prosthesis, and a history of venous thrombosis were the risk factors for venous thrombosis after hip arthroplasty. Conclusions This study suggests that female sex, age over 70 years, hypertension, a BMI of 25 or higher, duration of operation, stroke, mechanical prevention only, use of a cemented prosthesis, and a history of venous thrombosis are risk factors for venous thrombosis following hip arthroplasty. Clinical trial number not applicable.https://doi.org/10.1186/s12891-025-08764-zHip arthroplastyRisk factorsMeta-AnalysisSystematic reviewVenous thrombosis
spellingShingle Wang Huang
Weiwei Hu
Bangguo Lei
Weichen Huang
Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis
BMC Musculoskeletal Disorders
Hip arthroplasty
Risk factors
Meta-Analysis
Systematic review
Venous thrombosis
title Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis
title_full Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis
title_fullStr Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis
title_full_unstemmed Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis
title_short Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis
title_sort risk factors for venous thrombosis after hip arthroplasty a meta analysis
topic Hip arthroplasty
Risk factors
Meta-Analysis
Systematic review
Venous thrombosis
url https://doi.org/10.1186/s12891-025-08764-z
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