Creatine mitigates neurogenesis impairment caused by defective DcpS decapping
Abstract Biallelic mutations in the DCPS gene disrupting the decapping activity of the scavenger decapping protein DcpS, leads to neurodevelopmental deficiencies and intellectual disability. However, the molecular basis for the neurogenesis defects in these individuals remains unknown. Here we show...
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| Main Authors: | Jun Yang, Geeta Palsule, Xinfu Jiao, Jaime S. Messenger, Ronald P. Hart, Megerditch Kiledjian |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-02961-5 |
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