A case of infective endocarditis caused by beta-lactam resistant Streptococcus alactolyticus

Background: Streptococcus alactolyticus is a rare cause of human infections, with limited reports of infective endocarditis (IE). Case report: We present a case of a 68-year-old male with severe aortic stenosis who developed S. alactolyticus associated IE resistant to beta-lactams. Initial treatment...

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Main Authors: Melina Ntoga, Vasileios Emmanouil, Eirini Terzi, Vasilios Petrakis, Periklis Panagopoulos, Dimitrios Papazoglou
Format: Article
Language:English
Published: SMC MEDIA SRL 2025-04-01
Series:European Journal of Case Reports in Internal Medicine
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Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/5367
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author Melina Ntoga
Vasileios Emmanouil
Eirini Terzi
Vasilios Petrakis
Periklis Panagopoulos
Dimitrios Papazoglou
author_facet Melina Ntoga
Vasileios Emmanouil
Eirini Terzi
Vasilios Petrakis
Periklis Panagopoulos
Dimitrios Papazoglou
author_sort Melina Ntoga
collection DOAJ
description Background: Streptococcus alactolyticus is a rare cause of human infections, with limited reports of infective endocarditis (IE). Case report: We present a case of a 68-year-old male with severe aortic stenosis who developed S. alactolyticus associated IE resistant to beta-lactams. Initial treatment with vancomycin and gentamicin led to temporary improvement, but the patient later developed complications, including splenic infarction and an aortic root abscess. Despite intensified antimicrobial therapy, he ultimately succumbed to multiorgan failure. Conclusion: This case underscores the importance of early identification of resistant pathogens, appropriate antibiotic selection, and vigilant monitoring for complications. The rising incidence of beta-lactam resistance in streptococcal infections highlights the need for ongoing epidemiological surveillance and research to optimize treatment strategies.
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id doaj-art-cd1d6a9cdade408cbd9fca2673ccdf64
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issn 2284-2594
language English
publishDate 2025-04-01
publisher SMC MEDIA SRL
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series European Journal of Case Reports in Internal Medicine
spelling doaj-art-cd1d6a9cdade408cbd9fca2673ccdf642025-08-20T02:13:56ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942025-04-0110.12890/2025_0053674902A case of infective endocarditis caused by beta-lactam resistant Streptococcus alactolyticusMelina Ntoga0Vasileios Emmanouil1Eirini Terzi2Vasilios Petrakis3Periklis Panagopoulos4Dimitrios Papazoglou5Department of Infectious Diseases, Second University Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupoli, GreeceDepartment of Medicine, School of Health Sciences, Democritus University of Thrace, Alexandroupoli, GreeceDepartment of Infectious Diseases, Second University Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupoli, GreeceDepartment of Infectious Diseases, Second University Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupoli, GreeceDepartment of Infectious Diseases, Second University Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupoli, GreeceDepartment of Infectious Diseases, Second University Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupoli, GreeceBackground: Streptococcus alactolyticus is a rare cause of human infections, with limited reports of infective endocarditis (IE). Case report: We present a case of a 68-year-old male with severe aortic stenosis who developed S. alactolyticus associated IE resistant to beta-lactams. Initial treatment with vancomycin and gentamicin led to temporary improvement, but the patient later developed complications, including splenic infarction and an aortic root abscess. Despite intensified antimicrobial therapy, he ultimately succumbed to multiorgan failure. Conclusion: This case underscores the importance of early identification of resistant pathogens, appropriate antibiotic selection, and vigilant monitoring for complications. The rising incidence of beta-lactam resistance in streptococcal infections highlights the need for ongoing epidemiological surveillance and research to optimize treatment strategies.https://www.ejcrim.com/index.php/EJCRIM/article/view/5367infective endocarditisstreptococcus alactolyticus
spellingShingle Melina Ntoga
Vasileios Emmanouil
Eirini Terzi
Vasilios Petrakis
Periklis Panagopoulos
Dimitrios Papazoglou
A case of infective endocarditis caused by beta-lactam resistant Streptococcus alactolyticus
European Journal of Case Reports in Internal Medicine
infective endocarditis
streptococcus alactolyticus
title A case of infective endocarditis caused by beta-lactam resistant Streptococcus alactolyticus
title_full A case of infective endocarditis caused by beta-lactam resistant Streptococcus alactolyticus
title_fullStr A case of infective endocarditis caused by beta-lactam resistant Streptococcus alactolyticus
title_full_unstemmed A case of infective endocarditis caused by beta-lactam resistant Streptococcus alactolyticus
title_short A case of infective endocarditis caused by beta-lactam resistant Streptococcus alactolyticus
title_sort case of infective endocarditis caused by beta lactam resistant streptococcus alactolyticus
topic infective endocarditis
streptococcus alactolyticus
url https://www.ejcrim.com/index.php/EJCRIM/article/view/5367
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