Evaluation of self medication practices and prescription patterns in patients of chronic kidney disease: A cross-sectional, questionnaire based study
Background: Pharmacotherapy of chronic kidney disease (CKD) consists of prescribing myriad of drugs such as antihypertensives, antidiabetics, and phosphate binders to delay disease progression and control the comorbidities, resulting in inherent variability in prescriptions. In addition, tendency to...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Perspectives in Clinical Research |
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| Online Access: | https://journals.lww.com/10.4103/picr.picr_308_23 |
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| author | Raakhi K Tripathi Chaitali Pilliwar Snehalata V. Gajbhiye Sujeet K. Bhilwade Tukaram Jamale |
| author_facet | Raakhi K Tripathi Chaitali Pilliwar Snehalata V. Gajbhiye Sujeet K. Bhilwade Tukaram Jamale |
| author_sort | Raakhi K Tripathi |
| collection | DOAJ |
| description | Background:
Pharmacotherapy of chronic kidney disease (CKD) consists of prescribing myriad of drugs such as antihypertensives, antidiabetics, and phosphate binders to delay disease progression and control the comorbidities, resulting in inherent variability in prescriptions. In addition, tendency to self-medicate may further aggravate the condition. Hence, the present study was planned to assess self-medication practices and variability in prescription patterns in CKD patients.
Methodology:
A cross-sectional, questionnaire-based study approved by the ethics committee was conducted in CKD patients attending the nephrology outpatient department. The prescription details which included drug name, dosage form, dose, frequency, duration, and dosage instructions were recorded and prescription completeness was checked. To assess the tendency of CKD patients to self-medicate, each patient was administered a prevalidated [Content Validity Ratio (CVR) = 0.76] 8-item questionnaire which had dichotomous responses “Yes” and “No” and was scored as 2 and 0, respectively (total score 16).
Results:
Three hundred CKD patients (150 on hemodialysis and 150 nondialysis) yielded 300 prescriptions with 1272 drugs. It was evident that 33% of patients did self-medicate themselves with analgesics, and the mean score (7.81 ± 3.01) of self-medication practices was perceived significantly higher in the nondialysis group (8.41 ± 3.46). The most common classes of drugs prescribed in CKD patients were calcium channel blockers (41%), antidiabetic drugs (39%), diuretics (35%), gastrointestinal drugs (35%), and multivitamins (27%), with the average number of drugs being 5.84 ± 0.51.
Conclusion:
Nearly one-third of CKD patients were self-medicating with paracetamol, nonsteroidal anti-inflammatory drugs; more in the nondialysis group emphasizing reinforcement of patient education programs. The most common drugs prescribed were amlodipine, followed by metformin, and the average number of drugs was less in our setting, indicating vigilant dose prescribing in CKD patients. |
| format | Article |
| id | doaj-art-cd1b376103294c6da5f12568a483ea9a |
| institution | OA Journals |
| issn | 2229-3485 2229-5488 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Perspectives in Clinical Research |
| spelling | doaj-art-cd1b376103294c6da5f12568a483ea9a2025-08-20T02:34:24ZengWolters Kluwer Medknow PublicationsPerspectives in Clinical Research2229-34852229-54882025-01-01161233010.4103/picr.picr_308_23Evaluation of self medication practices and prescription patterns in patients of chronic kidney disease: A cross-sectional, questionnaire based studyRaakhi K TripathiChaitali PilliwarSnehalata V. GajbhiyeSujeet K. BhilwadeTukaram JamaleBackground: Pharmacotherapy of chronic kidney disease (CKD) consists of prescribing myriad of drugs such as antihypertensives, antidiabetics, and phosphate binders to delay disease progression and control the comorbidities, resulting in inherent variability in prescriptions. In addition, tendency to self-medicate may further aggravate the condition. Hence, the present study was planned to assess self-medication practices and variability in prescription patterns in CKD patients. Methodology: A cross-sectional, questionnaire-based study approved by the ethics committee was conducted in CKD patients attending the nephrology outpatient department. The prescription details which included drug name, dosage form, dose, frequency, duration, and dosage instructions were recorded and prescription completeness was checked. To assess the tendency of CKD patients to self-medicate, each patient was administered a prevalidated [Content Validity Ratio (CVR) = 0.76] 8-item questionnaire which had dichotomous responses “Yes” and “No” and was scored as 2 and 0, respectively (total score 16). Results: Three hundred CKD patients (150 on hemodialysis and 150 nondialysis) yielded 300 prescriptions with 1272 drugs. It was evident that 33% of patients did self-medicate themselves with analgesics, and the mean score (7.81 ± 3.01) of self-medication practices was perceived significantly higher in the nondialysis group (8.41 ± 3.46). The most common classes of drugs prescribed in CKD patients were calcium channel blockers (41%), antidiabetic drugs (39%), diuretics (35%), gastrointestinal drugs (35%), and multivitamins (27%), with the average number of drugs being 5.84 ± 0.51. Conclusion: Nearly one-third of CKD patients were self-medicating with paracetamol, nonsteroidal anti-inflammatory drugs; more in the nondialysis group emphasizing reinforcement of patient education programs. The most common drugs prescribed were amlodipine, followed by metformin, and the average number of drugs was less in our setting, indicating vigilant dose prescribing in CKD patients.https://journals.lww.com/10.4103/picr.picr_308_23medicationnephrotoxicitynonsteroidal anti-inflammatory drugprescription |
| spellingShingle | Raakhi K Tripathi Chaitali Pilliwar Snehalata V. Gajbhiye Sujeet K. Bhilwade Tukaram Jamale Evaluation of self medication practices and prescription patterns in patients of chronic kidney disease: A cross-sectional, questionnaire based study Perspectives in Clinical Research medication nephrotoxicity nonsteroidal anti-inflammatory drug prescription |
| title | Evaluation of self medication practices and prescription patterns in patients of chronic kidney disease: A cross-sectional, questionnaire based study |
| title_full | Evaluation of self medication practices and prescription patterns in patients of chronic kidney disease: A cross-sectional, questionnaire based study |
| title_fullStr | Evaluation of self medication practices and prescription patterns in patients of chronic kidney disease: A cross-sectional, questionnaire based study |
| title_full_unstemmed | Evaluation of self medication practices and prescription patterns in patients of chronic kidney disease: A cross-sectional, questionnaire based study |
| title_short | Evaluation of self medication practices and prescription patterns in patients of chronic kidney disease: A cross-sectional, questionnaire based study |
| title_sort | evaluation of self medication practices and prescription patterns in patients of chronic kidney disease a cross sectional questionnaire based study |
| topic | medication nephrotoxicity nonsteroidal anti-inflammatory drug prescription |
| url | https://journals.lww.com/10.4103/picr.picr_308_23 |
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